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261730 Aurka

261730

Aurka

aurora kinase A

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition aurora kinase A

研究结论

Date Results Publications
2020-05-23 12:47:00 AURKA ubiquitination influences mitochondrial dysfunction and suppresses the occurrence of OA via degradation of SOD2. 30811038
2016-05-14 11:36:00 AURKA upregulation by Nkx6.1 results in phosphorylation and degradation of p53, thus removing a key inhibitory factor and permitting engagement of the beta-cell proliferation pathway. 26030060
2015-08-01 10:07:00 This study suggests that KRC-108 has potential for development as an anti-tumor agent, although further studies are needed. 25912878
2011-12-10 10:26:00 These results demonstrate a direct positive role of estrogen in regulating Aurora-A expression through activation of the ERalpha-GATA-3 signaling cascade 21761347
2010-01-25 11:33:00 Data show that Aurora A interacts directly with the atypical protein kinase C binding domain of Par3 and phosphorylates it at serine 962. 19812038

名称对应

Type IDs
Synonymous ARK-1, Stk6
Gene
UniProtKB-ID: Q3MHU2_RAT
UniprotKB: Q3MHU2
UniParc: UPI0000250234
EMBL: AC131024, CH474062, BC104676
Ensembl: ENSRNOG00000004479
KO: rno:261730
Nucleutide sequences
EMBL-CDS: AAI04677.1, EDL85147.1, EDL85148.1
Gene_ORFName: rCG_40899
Ensembl_TRS: ENSRNOT00000055102
Protein sequencees
Ensembl_PRO: ENSRNOP00000051977
RefSeq: NP_695208.2, XP_006235737.1, XP_006235738.1
Others
UniRef100: UniRef100_Q3MHU2
UniRef90: UniRef90_P97477
UniRef50: UniRef50_O14965
UniGene: Rn.161874

全选

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研究热度

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