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261726 TIPRL

261726

TIPRL

TOR signaling pathway regulator

protein-coding

Homo sapiens

基因描述

Type Description
Definition TOR signaling pathway regulator

研究结论

Date Results Publications
2020-11-21 13:20:00 The positive correlation of TIPRL with LC3 and CD133 contributes to cancer aggressiveness: potential biomarkers for early liver cancer. 31727942
2020-09-12 16:04:00 TIPRL potentiates survival of lung cancer by inducing autophagy through the eIF2alpha-ATF4 pathway. 31862913
2019-03-09 10:41:00 MPC2 rs10489202 was genome-wide significantly associated with schizophrenia. The expression quantitative trait loci analysis in lymphoblastoid cell lines from East Asian donors revealed that MPC2 rs10489202 was specifically and significantly associated with the expression of TIPRL gene. 30087317
2016-07-16 11:06:00 overexpression of TIPRL promotes phosphorylation of H2AX, and increases gamma-H2AX positive foci in response to DNA damage, whereas knockdown of TIPRL inhibits gamma-H2AX phosphorylation 26717153
2013-11-16 10:04:00 Unlike yeast TIP41, TIPRL has a positive effect on mTORC1 signaling through the association with PP2Ac. 23892082

名称对应

Type IDs
Synonymous TIP, TIP41, TIPRL1
Gene
UniProtKB-ID: TIPRL_HUMAN
UniprotKB: O75663
UniParc: UPI0000071605, UPI000007415F
EMBL: AK313520, BX648646, CH471067, AL049670, AB097034, BC009506, AL021397
Ensembl: ENSG00000143155
KO: hsa:261726
Nucleutide sequences
EMBL-CDS: CAB41244.1, CAI46265.1, BAC77387.1, EAW90821.1, BAG36300.1, AAH09506.1
Ensembl_TRS: ENST00000367830, ENST00000367833
Protein sequencees
Ensembl_PRO: ENSP00000356807, ENSP00000356804
RefSeq: NP_690866.1, NP_001026970.1
Others
UniRef100: UniRef100_O75663
UniRef90: UniRef90_O75663
UniRef50: UniRef50_O75663
UniGene: Hs.209431
CCDS: CCDS30935.1, CCDS1270.1

全选

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