| Type | Description |
|---|---|
| Definition | SUMO specific peptidase 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:16:00 | SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes. | 32049023 |
| 2020-07-11 11:39:00 | SUMO1-catalyzed SUMOylation and SENP3-mediated deSUMOylation of NLRP3 orchestrate the inflammasome activation. | 31914638 |
| 2020-02-28 17:20:00 | Recruitment of the protein complex 5FMC to Zbp-89, a zinc-finger transcription factor, affects its sumoylation status and transactivation potential.[5FMC] | 22872859 |
| 2019-12-21 10:54:00 | we performed ischemia and ischemia-reperfusion experiments in the cardiomyocyte H9C2 cell line. Similar to whole hearts, ischemia induced a decrease in cytosolic SENP3. Furthermore, shRNA-mediated knockdown of SENP3 led to an increase in the rate of cell death upon reperfusion. | 30973885 |
| 2019-10-05 10:38:00 | SENP3 expression level decreased in HBV-infected hepatocytes in various models including HepG2-NTCP cell lines and a humanized mouse model. Downregulation of SENP3 reduced HBV replication and boosted host protein translation. | 30640896 |
| Type | IDs |
|---|---|
| Synonymous | SMT3IP1, SSP3, Ulp1 |
| Gene |
UniProtKB-ID:
SENP3_HUMAN
UniprotKB:
Q9H4L4
UniParc:
UPI0000163BE7
EMBL:
AL050283,
BC048306,
AY008763,
BC080658,
AL834294,
AF199459
Ensembl:
ENSG00000161956
KO:
hsa:26168
|
| Nucleutide sequences |
EMBL-CDS:
CAD38967.1,
AAL25652.1,
AAG33252.1,
AAH80658.1,
CAB43384.2,
AAH48306.1
Ensembl_TRS:
ENST00000429205,
ENST00000321337
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000403712,
ENSP00000314029
RefSeq:
NP_056485.2
|
| Others |
UniRef100:
UniRef100_Q9H4L4
UniRef90:
UniRef90_Q9H4L4
UniRef50:
UniRef50_Q9H4L4
UniGene:
Hs.513926,
Hs.733104
CCDS:
CCDS73958.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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