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26133 TRPC4AP

26133

TRPC4AP

transient receptor potential cation channel subfamily C member 4 associated protein

protein-coding

Homo sapiens

基因描述

Type Description
Definition transient receptor potential cation channel subfamily C member 4 associated protein

研究结论

Date Results Publications
2019-03-30 11:23:00 Hepatocyte TRUSS promotes pathological stimuli-induced non alcoholic fatty liver disease and metabolic disorders, through activation of NF-kappaB by promoting ubiquitination and degradation of IkappaBalpha 29704259
2016-05-28 10:04:00 TRUSS is a novel substrate of E3 ligase Skp2. 26038816
2011-08-29 07:52:00 The latent classification method of analysis showed that the TRPC4AP H1 haplotype was characteristic of Alzheimer's patients, with ages-of-onset between 66 and 80 years. 19059308
2010-10-23 10:53:00 These findings suggest that TNF-R1, TRUSS, and TRPC4 augment Ca(2+) loading of endoplasmic reticulum Ca(2+) stores in the context of m1AchR stimulation 20458742
2010-07-05 11:46:00 TRPC4AP/TRUSS binds specifically to the Myc C terminus and promotes its ubiquitination and destruction through the recognition of evolutionarily conserved domains in the Myc N terminus 20551172

名称对应

Type IDs
Synonymous C20orf188, PPP1R158, TRRP4AP, TRUSS
Gene
UniProtKB-ID: TP4AP_HUMAN, B4DW48_HUMAN
UniprotKB: Q8TEL6, B4DW48
UniParc: UPI000002B4A0, UPI000004FADD, UPI00017A81E4, UPI000023C3E3
EMBL: BC013144, AK074106, AL117480, AK301368, CH471077, BC001323, BC008836, AL132825, AB590540
Ensembl: ENSG00000100991
KO: hsa:26133
Nucleutide sequences
EMBL-CDS: CAB55953.1, AAH13144.1, EAW76233.1, EAW76235.1, AAH08836.2, BAJ20695.1, EAW76229.1, AAH01323.1, BAB84932.1, EAW76234.1, BAG62910.1
Ensembl_TRS: ENST00000252015, ENST00000451813
Protein sequencees
Ensembl_PRO: ENSP00000252015, ENSP00000400614
RefSeq: XP_016883289.1, XP_016883290.1, XP_024307636.1, NP_955400.1, NP_056453.1, XP_016883288.1
Others
UniRef100: UniRef100_Q8TEL6, UniRef100_B4DW48
UniRef90: UniRef90_Q8TEL6, UniRef90_A0A2I2ZFK0
UniRef50: UniRef50_Q8TEL6, UniRef50_A0A0S7GCL2
UniGene: Hs.168073
CCDS: CCDS46591.1, CCDS13246.1

全选

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