| Type | Description |
|---|---|
| Definition | KIF1 binding protein |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:34:00 | The mechanism of kinesin inhibition by kinesin-binding protein. | 33252036 |
| 2020-04-18 12:00:00 | KBP acts as a protein buffer in mitosis, protecting cells from excessive KIF18A and KIF15 activity to promote accurate chromosome segregation. | 30709852 |
| 2017-09-09 10:31:00 | Both Kif15 and KBP are required for the alignment of all the chromosomes to the metaphase plate and the assembly of stable kinetochore fibers of the correct length. | 28445502 |
| 2016-12-24 11:07:00 | Data suggest that KBP functions as a kinesin inhibitor that modulates MT-based cargo motility and depolymerizing activity of a subset of kinesin motors. We propose that misregulation of KBP-controlled kinesin motors may represent the underlying molecular mechanism that contributes to the neuropathological defects observed in Goldberg-Shprintzen syndrome patients. | 26948876 |
| 2014-06-28 11:18:00 | A report on fetal cases with a homozygous mutation in KBP gene in a consanguineous Pakistani family with isolated polymicrogyria. | 24072599 |
| Type | IDs |
|---|---|
| Synonymous | KBP, KIAA1279, TTC20 |
| Gene |
UniProtKB-ID:
KBP_HUMAN
UniprotKB:
Q96EK5
UniParc:
UPI000006FCAF
EMBL:
BC012180,
AB033105,
AL050190,
AL359844,
AK291343
Ensembl:
ENSG00000198954
KO:
hsa:26128
|
| Nucleutide sequences |
EMBL-CDS:
AAH12180.1,
BAA86593.1,
BAF84032.1,
CAB43311.1
Ensembl_TRS:
ENST00000361983
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354848
RefSeq:
NP_056449.1,
XP_016871556.1
|
| Others |
UniRef100:
UniRef100_Q96EK5
UniRef90:
UniRef90_Q96EK5
UniRef50:
UniRef50_Q96EK5
UniGene:
Hs.279580
CCDS:
CCDS7284.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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