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26118 WSB1

26118

WSB1

WD repeat and SOCS box containing 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition WD repeat and SOCS box containing 1

研究结论

Date Results Publications
2019-06-15 10:36:00 WSB-1 may be an important regulator of aggressive metastatic disease in hormone receptor-negative breast cancer. WSB-1 could therefore represent a novel regulator and therapeutic target for secondary breast cancer in these patients. 29540773
2018-01-13 14:22:00 howed that miR-592 directly binds to the 3'-UTR of the WSB1 gene, thus disrupting hypoxia inducible factor-1alpha (HIF-1alpha) protein stabilization 27153552
2017-12-23 11:59:00 WSB1 is one of the key players of early oncogenic events through ATM degradation and destruction of the tumorigenesis barrier. 27958289
2017-02-04 11:47:00 WSB1 in glucose metabolism, and perhaps in mediating the Warburg effect in cancer cells by maintaining the function of HIF1. 27542736
2016-02-27 10:16:00 WSB1 up-regulates the expression of HIF-1alpha's target genes and promotes cancer invasion and metastasis through its effect on pVHL 26545811

名称对应

Type IDs
Synonymous SWIP1, WSB-1
Gene
UniProtKB-ID: WSB1_HUMAN, Q8NC76_HUMAN, A0A024QZ36_HUMAN, A0A024QZ51_HUMAN
UniprotKB: Q9Y6I7, Q8NC76, A0A024QZ36, A0A024QZ51
UniParc: UPI0000072BAB, UPI000002B6EB, UPI000013FEEC, UPI00000706B9, UPI0000031568
EMBL: AF072880, AF106684, AF106683, AF240696, CH471159, BC021110, AL110243, AF069313, AK074917, AL110269, AF112205
Ensembl: ENSG00000109046
KO: hsa:26118
Nucleutide sequences
EMBL-CDS: AAD20954.2, AAF17193.1, AAH21110.1, CAB53693.1, AAD28808.1, AAF82746.1, CAB53708.2, AAD43036.1, AAD43037.1, BAC11291.1, EAW51028.1, EAW51029.1, EAW51030.1, EAW51027.1
Gene_ORFName: hCG_28214, hCG_28214
Ensembl_TRS: ENST00000262394, ENST00000348811
Protein sequencees
Ensembl_PRO: ENSP00000262394, ENSP00000327055
RefSeq: XP_005258020.1, NP_599027.1, NP_056441.6, XP_016879924.1, XP_016879925.1, XP_016879923.1, NP_001335279.1
Others
UniRef100: UniRef100_Q9Y6I7, UniRef100_Q8NC76, UniRef100_A0A024QZ36
UniRef90: UniRef90_A0A096P367, UniRef90_Q9Y6I7
UniRef50: UniRef50_Q9Y6I7, UniRef50_A0A096P367
UniGene: Hs.446017
CCDS: CCDS11221.1, CCDS11220.1

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