| Type | Description |
|---|---|
| Definition | chromatin target of PRMT1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 12:38:00 | These findings first suggest that CHTOP, as a highly expressed protein in ovarian cancer, is closely associated with the malignant phenotypes of epithelial ovarian cancer cells, including metastasis, chemoresistance, and stemness, which highlights a promising role of CHTOP in ovarian cancer targeted therapy. | 30910850 |
| 2017-06-10 12:44:00 | the cellular level of Chtop is autoregulated via Int2 retention of its own mRNA, which subsequently undergoes NMD. | 27683223 |
| 2015-07-25 10:08:00 | Results suggest that 5hmC plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex to selective sites on the chromosome, where it methylates H4R3 and activates the transcription of cancer-related genes. | 25284789 |
| 2014-02-08 11:49:00 | a spatial map is produced in living cells of the sites for the interaction of two TREX subunits, Alyref and Chtop, with Nxf1. | 23826332 |
| 2013-04-06 13:05:00 | Chtop is a component of the dynamic TREX mRNA export complex that, along with Alyref, activates the ATPase and RNA helicase activities of Uap56. | 23299939 |
| Type | IDs |
|---|---|
| Synonymous | C10orf77, C1orf77, FL-SRAG, FOP, SRAG, SRAG-3, SRAG-5, pp7704 |
| Gene |
UniProtKB-ID:
CHTOP_HUMAN,
A0A087X1B7_HUMAN
UniprotKB:
Q9Y3Y2,
A0A087X1B7
UniParc:
UPI00000467F6,
UPI00002047F8,
UPI0000470BC6,
UPI00000467E4
EMBL:
BC120962,
BC002733,
BC070027,
AF318362,
AL162258,
AL512704,
CH471121,
BC108721,
BC059949,
AL050260,
AF261137,
BC120961
Ensembl:
ENSG00000160679
KO:
hsa:26097
|
| Nucleutide sequences |
EMBL-CDS:
AAI20962.1,
AAH59949.1,
AAH70027.1,
AAG44673.1,
CAC21650.2,
AAH02733.1,
AAI20963.1,
AAI08722.1,
EAW53290.1,
EAW53295.1,
CAB43362.2,
AAL55869.1
Gene_ORFName:
PP7704,
HT031
Ensembl_TRS:
ENST00000368690,
ENST00000403433,
ENST00000368694,
ENST00000614256
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357683,
ENSP00000357679,
ENSP00000385228,
ENSP00000484038
RefSeq:
NP_056422.2,
NP_001304006.1,
NP_001193541.1,
XP_016856482.1,
NP_001231593.1
|
| Others |
UniRef100:
UniRef100_Q9Y3Y2,
UniRef100_A0A087X1B7
UniRef90:
UniRef90_A0A2I3HTA6,
UniRef90_Q9Y3Y2
UniRef50:
UniRef50_Q9Y3Y2,
UniRef50_A0A2I3HTA6
UniGene:
Hs.611057
CCDS:
CCDS81380.1,
CCDS1048.1,
CCDS72917.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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