| Type | Description |
|---|---|
| Definition | GRB10 interacting GYF protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:59:00 | GIGYF2 and 4EHP Inhibit Translation Initiation of Defective to Assist Ribosome-Associated Quality Control. | 32726578 |
| 2019-07-27 12:58:00 | GIGYF2 has two distinct mechanisms of repression: one depends on 4EHP binding and mainly affects translation; the other is 4EHP-independent and involves the CCR4/NOT complex and its deadenylation activity. | 29554310 |
| 2017-10-21 11:54:00 | genetic analyses of indel loci in ACE, DJ-1, and GIGYF2 genes, was performed to explore the potential contribution of insertion (I)/deletion (D) polymorphisms (indels) to the risk of PD in a Chinese population. | 28873462 |
| 2017-05-13 17:14:00 | Full-length GIGYF2 coimmunoprecipitates with AGO2 in human cells, and upon tethering to a reporter mRNA, GIGYF2 exhibits strong, dose-dependent silencing activity, involving both mRNA destabilization and translational repression. | 27157137 |
| 2016-10-01 12:36:00 | required, this finding may shed light on the GIGYF2-associated mechanisms that lead to PD and suggests insulin dysregulation as a disease-specific mechanism for both PD and cognitive dysfunction. | 26134514 |
| Type | IDs |
|---|---|
| Synonymous | GYF2, PARK11, PERQ2, PERQ3, TNRC15 |
| Gene |
UniProtKB-ID:
GGYF2_HUMAN
UniprotKB:
Q6Y7W6
UniParc:
UPI00003FEC8F,
UPI00001BD8AE,
UPI00015B9BB4,
UPI0002A7BC57
EMBL:
BX538321,
AK001739,
BC136251,
BX537885,
AC016692,
BC008072,
CH471063,
AB014542,
BX538172,
AC064852,
BC146775,
AY176045
Ensembl:
ENSG00000204120
KO:
hsa:26058
|
| Nucleutide sequences |
EMBL-CDS:
CAD97881.1,
AAI46776.1,
AAI36252.1,
BAA91873.1,
AAH08072.2,
CAD98095.1,
EAW71016.1,
AAO46889.1,
BAA31617.2
Ensembl_TRS:
ENST00000409451,
ENST00000409196,
ENST00000409547,
ENST00000373563
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000386537,
ENSP00000362664,
ENSP00000387170,
ENSP00000387070
RefSeq:
NP_001096618.1,
NP_056390.2,
NP_001096617.1,
NP_001096616.1
|
| Others |
UniRef100:
UniRef100_Q6Y7W6
UniRef90:
UniRef90_Q6Y7W6
UniRef50:
UniRef50_Q6Y7W6
UniGene:
Hs.565319
CCDS:
CCDS46542.1,
CCDS33401.1,
CCDS46543.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员