| Type | Description |
|---|---|
| Definition | protein phosphatase 1 regulatory subunit 16B |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 12:51:00 | The TIMAP inhibits myosin phosphatase activity in ECs by competing with MYPT1 for PP1cbeta and blocking the PP1cbeta active site. | 31315927 |
| 2018-07-07 11:22:00 | TIMAP is the versatile protein phosphatase 1 regulator in endothelial cells. (Review) | 29140585 |
| 2017-11-04 12:39:00 | NF2 localizes in nucleus when Ser518 is not phosphorylated, while phosphorylated form is present in cytoplasm and plasma membrane. Data suggest that binding of NF2 to TIMAP and EBP50 is critical in nuclear localization of NF2. (NF2 = neurofibromin 2; TIMAP = TGF-beta-inhibited membrane-associated protein; EBP50 = Ezrin-Radixin-Mosein binding phosphoprotein 50) | 27871951 |
| 2017-06-24 11:36:00 | phosphorylation of TIMAP on Ser331 by represents a new mechanism of endothelial barrier regulation, through the inhibition of phospho-ERM dephosphorylation | 27939168 |
| 2016-12-24 11:57:00 | Results indicate that ECE-1 is a TIMAP-PP1c substrate and this phosphatase complex has an important role in endothelin-1 production of EC through the regulation of ECE-1 activity. | 26806547 |
| Type | IDs |
|---|---|
| Synonymous | ANKRD4, TIMAP |
| Gene |
UniProtKB-ID:
PP16B_HUMAN
UniprotKB:
Q96T49
UniParc:
UPI0000132059,
UPI0000D6108E
EMBL:
AL031657,
BC131801,
BC152467,
CH471077,
AL023803,
AF362910,
AL121889,
AB020630,
AB177855
Ensembl:
ENSG00000101445
KO:
hsa:26051
|
| Nucleutide sequences |
EMBL-CDS:
AAI31802.1,
EAW76009.1,
BAD66833.1,
BAA74846.2,
AAI52468.1,
AAK52796.1
Ensembl_TRS:
ENST00000373331,
ENST00000299824
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362428,
ENSP00000299824
RefSeq:
XP_016883274.1,
XP_011527070.1,
NP_056383.1,
NP_001166206.1,
XP_011527071.1
|
| Others |
UniRef100:
UniRef100_Q96T49
UniRef90:
UniRef90_Q96T49
UniRef50:
UniRef50_Q96T49
UniGene:
Hs.45719
CCDS:
CCDS54462.1,
CCDS13309.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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