| Type | Description |
|---|---|
| Definition | membrane associated guanylate kinase, WW and PDZ domain containing 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:01:00 | Integrated analyses identify miR-34c-3p/MAGI3 axis for the Warburg metabolism in hepatocellular carcinoma. | 32080912 |
| 2018-12-01 10:11:00 | Study shows that MAGI3 undergoes premature polyadenylation (pPA) at the intron immediately downstream of its large internal exon, which is normally highly modified by N(6)-methyladenosine (m(6)A). In breast cancer cells that upregulate MAGI3 (pPA) , m(6)A levels in the large internal exon of MAGI3 are significantly reduced compared to cells that do not express MAGI3 (pPA). MAGI3 (pPA) transcripts are depleted of m(6)A. | 29362392 |
| 2018-03-31 10:38:00 | Our findings lend support to a genetic basis for modulation of intestinal epithelial barrier in IBD, and we have identified MAGI3 as a new candidate gene for IBD. | 28545409 |
| 2017-11-11 12:33:00 | The altered mRNA isoform, called MAGI3(pPA), produces a truncated protein that acts in a dominant-negative manner to prevent full-length MAGI3 from interacting with the YAP oncoprotein, thereby relieving YAP inhibition and promoting malignant transformation of human mammary epithelial cells. | 27205883 |
| 2016-10-29 11:17:00 | Results identify MAGI3 as a novel tumor suppressor and provide insight into the pathogenesis of glioma. | 26452219 |
| Type | IDs |
|---|---|
| Synonymous | MAGI-3, dJ730K3.2 |
| Gene |
UniProtKB-ID:
MAGI3_HUMAN
UniprotKB:
Q5TCQ9
UniParc:
UPI000013D18B,
UPI00001AEE70,
UPI00004589AE,
UPI000036656D
EMBL:
AF257238,
AB046854,
BC130409,
AL133517,
CH471122,
AF213259,
AL365225,
AL390759,
AL389921,
AK026417
Ensembl:
ENSG00000081026
KO:
hsa:260425
|
| Nucleutide sequences |
EMBL-CDS:
AAI30410.1,
BAB13460.1,
EAW56559.1,
AAG43837.1,
BAB15479.1,
EAW56562.1,
EAW56563.1,
EAW56560.1,
AAG24545.1,
EAW56561.1
Ensembl_TRS:
ENST00000369615,
ENST00000369617,
ENST00000307546,
ENST00000369611
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358630,
ENSP00000358624,
ENSP00000304604,
ENSP00000358628
RefSeq:
NP_690864.2,
NP_001136254.1,
XP_005270794.1,
XP_011539510.1,
XP_016856463.1,
XP_016856464.1
|
| Others |
UniRef100:
UniRef100_Q5TCQ9
UniRef90:
UniRef90_Q5TCQ9
UniRef50:
UniRef50_Q5TCQ9
UniGene:
Hs.486189
CCDS:
CCDS860.1,
CCDS44196.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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