| Type | Description |
|---|---|
| Definition | tumor protein p63 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 12:40:00 | During early zebrafish embryonic development, p63 binds to enhancers associated to neural plate-expressing genes, where it limits Sox3 binding and neural gene expression. p63 binds enhancers associated to epidermis-expressing genes when they are in a non-accessible chromatin state, leading to its opening and epidermal gene expression. | 31296872 |
| 2014-06-21 11:11:00 | they unravel essential roles of TAp63 and p53 to promote both keratinocyte proliferation and their terminal differentiation by promoting Notch signalling and caspase 3 activity. | 24415949 |
| 2011-11-26 10:35:00 | the p63 transcription factor is upregulated to initiate this apoptotic pathway and directly activates puma transcription in response to ER stress. | 21920315 |
| 2010-01-21 00:00:00 | Early zebrafish embryos express a dominant-negative form of p63 (DeltaNp63), which accumulates in the nucleus just as epidermal growth begins. (p63) | 12015968 |
| 2010-01-21 00:00:00 | DeltaNp63 expression blocks neural development and promotes nonneural development, even in the absence of Bmp signaling. (DeltaNp63) | 12015969 |
| Type | IDs |
|---|---|
| Synonymous | DNp63, fc89f04, id:ibd3516, p63, tp73l, wu:fc89f04, wu:fk85h07, wu:fk88b02 |
| Gene |
UniProtKB-ID:
Q8JHZ6_DANRE,
Q8JFE3_DANRE,
Q8JHZ5_DANRE
UniprotKB:
Q8JHZ6,
Q8JFE3,
Q8JHZ5
UniParc:
UPI00000FB3F5,
UPI00000FCA4B,
UPI00000FC426
EMBL:
AF412284,
BX004773,
AF487944,
BX004878,
AF412285,
AF412283
Ensembl:
ENSDARG00000044356
KO:
dre:260407
|
| Nucleutide sequences |
EMBL-CDS:
AAN03690.1,
AAN03691.1,
AAM48108.1,
AAN03692.1
Ensembl_TRS:
ENSDART00000130799
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000107767
RefSeq:
NP_689454.1,
NP_694519.1,
NP_694518.1
|
| Others |
UniRef100:
UniRef100_Q8JHZ5,
UniRef100_Q8JFE3,
UniRef100_Q8JHZ6
UniRef90:
UniRef90_Q8JHZ6,
UniRef90_Q8JFE3,
UniRef90_Q8JHZ5
UniRef50:
UniRef50_O88898,
UniRef50_Q9JJP2-4,
UniRef50_Q9H3D4-4
UniGene:
Dr.32588
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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