| Type | Description |
|---|---|
| Definition | zinc finger protein 451 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:35:00 | Stress-induced nuclear condensation of NELF drives transcriptional downregulation. | 33548202 |
| 2018-09-01 10:25:00 | The findings of this study indicate that BC032020 suppresses the survival of PDAC cells by inhibiting ZNF451 expression. | 29532883 |
| 2018-03-10 11:30:00 | These findings uncover a ZNF451-TDP2-catalyzed and SUMO2-modulated pathway for direct resolution of TOP2 cleavage complex. | 28912134 |
| 2016-03-26 10:31:00 | The authors show that ZNF451 is SUMO2 specific and that SUMO modification of ZNF451 may contribute to activity by providing a second molecule of SUMO that interacts with E2. | 26524494 |
| 2014-03-29 10:13:00 | ZNF451 acts as a transcriptional corepressor for Smad3/4 and negatively regulates TGF-beta signaling. | 24324267 |
| Type | IDs |
|---|---|
| Synonymous | COASTER, dJ417I1.1 |
| Gene |
UniProtKB-ID:
ZN451_HUMAN,
Q96JY2_HUMAN,
B4DYS2_HUMAN
UniprotKB:
Q9Y4E5,
Q96JY2,
B4DYS2
UniParc:
UPI0000423BF4,
UPI00017A8176,
UPI000004A56F,
UPI0000072E53,
UPI000004A571
EMBL:
AY055204,
AB011148,
BC058853,
AK302577,
AK027805,
AL450489,
BC021712,
BC042450,
AB051489,
AL136311
Ensembl:
ENSG00000112200
KO:
hsa:26036
|
| Nucleutide sequences |
EMBL-CDS:
AAH58853.1,
BAB21793.1,
BAA25502.1,
AAH42450.1,
AAH21712.2,
AAL17975.1,
BAB55382.1,
BAG63834.1
Ensembl_TRS:
ENST00000370708,
ENST00000370706,
ENST00000357489
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000350083,
ENSP00000359742,
ENSP00000359740
RefSeq:
XP_011512763.1,
XP_011512762.1,
NP_001244202.1,
XP_005249051.1,
XP_011512765.1,
NP_001026794.1,
XP_011512764.1,
NP_056370.2
|
| Others |
UniRef100:
UniRef100_Q9Y4E5,
UniRef100_Q96JY2,
UniRef100_A0A2J8SSS9
UniRef90:
UniRef90_Q9Y4E5,
UniRef90_Q9Y4E5-4
UniRef50:
UniRef50_Q9Y4E5-4,
UniRef50_Q9Y4E5
UniGene:
Hs.485628,
Hs.705485
CCDS:
CCDS59026.1,
CCDS43477.1,
CCDS4960.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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