| Type | Description |
|---|---|
| Definition | hyaluronan synthase 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-01 10:16:00 | Fgf signaling is required early, from 6 to 10h pf,for has2 activation. Loss of has2 results inthe loss of the chondrogenic program resulting in postchordal neurocranial defects in Fgf loss-of-function embryos. Shh is not essential for this early activation of has2. | 27060628 |
| 2017-06-03 10:15:00 | propose here a rather unique role of Med10 in orchestrating cardiac valve formation by mediating Foxn4 dependent tbx2b transcription, expression of Has2 and subsequently proper development of the cardiac jelly | 27343557 |
| 2011-12-03 10:26:00 | identify Npnt as a novel upstream regulator of Bmp4-Has2 signaling that plays a crucial role in AV canal differentiation | 21937601 |
| 2011-10-29 10:21:00 | MiR-23 is both necessary and sufficient for restricting the number of endocardial cells that differentiate into endocardial cushion cells by inhibiting Has2 and extracellular hyaluronic acid production. | 21778427 |
| 2010-10-23 10:06:00 | data demonstrate that elevated glucose alone induces cardiac defects in zebrafish embryos by altering the expression pattern of tbx5, tbx20, and has2 in the hear | 20306498 |
| Type | IDs |
|---|---|
| Synonymous | DG42 |
| Gene |
UniProtKB-ID:
Q9DG41_DANRE
UniprotKB:
Q9DG41
UniParc:
UPI00000FBD99
EMBL:
BX936449,
BC100130,
AF190742
Ensembl:
ENSDARG00000036987
KO:
dre:260350
|
| Nucleutide sequences |
EMBL-CDS:
AAI00131.1,
AAG17180.1
Ensembl_TRS:
ENSDART00000053754
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000053753
RefSeq:
NP_705936.1
|
| Others |
UniRef100:
UniRef100_Q9DG41
UniRef90:
UniRef90_Q9DG41
UniRef50:
UniRef50_P70312
UniGene:
Dr.82516
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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