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26012 NSMF

26012

NSMF

NMDA receptor synaptonuclear signaling and neuronal migration factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition NMDA receptor synaptonuclear signaling and neuronal migration factor

研究结论

Date Results Publications
2019-03-23 12:24:00 These findings suggest a role for NELF in the regulation of the signaling pathway, which have important functions in GnRH neurons. 29050862
2014-09-20 12:21:00 The nuclear and non-nuclear NELF variant transcripts and proteins were identified, explaining variable NELF cellular localization. 24316376
2014-02-08 10:33:00 a model in which NELF recruits Pcf11 and NCoR1-GPS2-HDAC3 to paused RNAP II, reinforcing repression of HIV transcription and establishing a critical checkpoint for HIV transcription and latency. 23884411
2011-05-14 10:46:00 NELF is associated with normosmic idiopathic hypogonadotropic hypogonadism and Kallmann syndrome, either singly or in combination with a mutation in another gene. 21300340
2010-06-14 11:38:00 our findings implicate NELF as a nuclear protein involved in the developmental function of the reproductive axis. 20025934

名称对应

Type IDs
Synonymous HH9, NELF
Gene
UniProtKB-ID: NSMF_HUMAN, A8K7L5_HUMAN
UniprotKB: Q6X4W1, A8K7L5
UniParc: UPI00006633C1, UPI000035198F, UPI000035198D, UPI000035198E, UPI000006E086, UPI0000072C6C, UPI0000351990
EMBL: AK292030, AK074602, AL365502, BC110498, AY255132, AY255128, AY255129, BC072412, AK027474, CH471090, AY255130, AL389946, AL389944, AY255131, AL389945
Ensembl: ENSG00000165802
KO: hsa:26012
Nucleutide sequences
EMBL-CDS: BAB55139.1, CAB97525.1, CAB97542.1, CAB97524.1, AAP83580.1, AAI10499.1, BAC11086.1, AAP83578.1, AAP83576.1, AAP83577.1, AAH72412.1, AAP83579.1, EAW88393.1, EAW88391.1, BAF84719.1
Gene_ORFName: hCG_28443
Ensembl_TRS: ENST00000371472, ENST00000371474, ENST00000371475, ENST00000265663, ENST00000371473, ENST00000437259
Protein sequencees
Ensembl_PRO: ENSP00000360530, ENSP00000412007, ENSP00000360528, ENSP00000265663, ENSP00000360527, ENSP00000360529
RefSeq: XP_011516798.1, XP_005266118.1, NP_056352.3, XP_011516799.1, NP_001124443.1, NP_001171535.1, XP_016870086.1, NP_001124442.1, XP_005266119.1, NP_001124441.1
Others
UniRef100: UniRef100_A8K7L5, UniRef100_Q6X4W1
UniRef90: UniRef90_Q6X4W1, UniRef90_Q9EPI6
UniRef50: UniRef50_Q6X4W1, UniRef50_Q9EPI6
UniGene: Hs.455336
CCDS: CCDS7044.1, CCDS48067.1, CCDS48068.1, CCDS48069.1, CCDS55357.1

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研究热度

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