| Type | Description |
|---|---|
| Definition | RNA exonuclease 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 12:58:00 | Germline variant in REXO2 is a novel candidate gene in familial pheochromocytoma. | 32354376 |
| 2020-08-22 15:26:00 | Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA. | 32365187 |
| 2020-02-22 11:39:00 | Efficient RNA turnover by REXO2 is thus required to maintain promoter specificity and proper regulation of transcription in mammalian mitochondria. | 31588022 |
| 2019-06-15 11:49:00 | This study provides the molecular basis for human Rexo2, showing how it binds and degrades nanoRNA into nucleoside monophosphates and plays a crucial role in RNA salvage pathways in mammalian mitochondria. | 30926754 |
| 2017-01-28 10:33:00 | results demonstrate that 14-3-3sigma induces cisplatin resistance in esophageal squamous cell carcinoma cells | 26346170 |
| Type | IDs |
|---|---|
| Synonymous | CGI-114, REX2, RFN, SFN |
| Gene |
UniProtKB-ID:
ORN_HUMAN
UniprotKB:
Q9Y3B8
UniParc:
UPI0000E44571,
UPI000013D69D,
UPI00001699A6
EMBL:
BC107887,
BC105026,
AF151872,
AL110239,
AK223200,
CH471065,
BC143701,
CR533500,
BC105024,
AK312042
Ensembl:
ENSG00000076043
KO:
hsa:25996
|
| Nucleutide sequences |
EMBL-CDS:
BAD96920.1,
CAB53690.1,
EAW67250.1,
AAI05025.1,
AAD34109.1,
CAG38531.1,
BAG34979.1,
AAI05027.1,
AAI43702.1,
AAI07888.1
Gene_ORFName:
CGI-114
Ensembl_TRS:
ENST00000265881,
ENST00000611665
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265881,
ENSP00000480535
RefSeq:
NP_056338.2
|
| Others |
UniRef100:
UniRef100_Q9Y3B8
UniRef90:
UniRef90_Q9Y3B8
UniRef50:
UniRef50_Q9Y3B8
UniGene:
Hs.677190,
Hs.714231
CCDS:
CCDS8371.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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