| Type | Description |
|---|---|
| Definition | HIG1 hypoxia inducible domain family member 1A |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 11:39:00 | Higd1a, or its mimic, provides therapeutic options for the treatment of mitochondrial diseases. | 31914602 |
| 2020-05-30 13:48:00 | High Higd-1a expression is associated with proliferation of pancreatic cancer cells through a pERK/p27/pRB pathway. | 31310799 |
| 2019-12-21 12:20:00 | Higd1a plays positive roles in protecting cells from oxidative stress, and reactive oxygen species could induce Higd1a expression by upregulating PGC-1a and HIF-1a expressions. | 31089410 |
| 2013-11-30 12:02:00 | Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress. | 23646141 |
| 2013-11-16 11:52:00 | Data indicate that hypoxia-induced gene domain protein-1a (Higd-1a) inhibits Optic atrophy 1 (Opa1) cleavage and is required for mitochondrial fusion by virtue of its interaction with Opa1. | 23878241 |
| Type | IDs |
|---|---|
| Synonymous | HIG1, RCF1a |
| Gene |
UniProtKB-ID:
HIG1A_HUMAN
UniprotKB:
Q9Y241
UniParc:
UPI000020A587,
UPI00000373C8
EMBL:
BC009583,
BC009594,
BC070277,
BC000601,
BG400624,
CR457385,
AL110233,
AF077034,
AF145385
Ensembl:
ENSG00000181061
KO:
hsa:25994
|
| Nucleutide sequences |
EMBL-CDS:
AAH00601.1,
AAH70277.1,
CAG33666.1,
AAH09594.1,
AAH09583.1,
AAD33954.1,
CAB53686.1,
AAD27767.1
Gene_ORFName:
HSPC010
Ensembl_TRS:
ENST00000418900,
ENST00000321331,
ENST00000452906
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000398064,
ENSP00000402160,
ENSP00000319393
RefSeq:
NP_054775.2,
NP_001093138.1,
NP_001093139.1
|
| Others |
UniRef100:
UniRef100_Q9Y241
UniRef90:
UniRef90_Q9Y241
UniRef50:
UniRef50_Q9Y241
UniGene:
Hs.593134,
Hs.728813
CCDS:
CCDS46806.1,
CCDS43073.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员