| Type | Description |
|---|---|
| Definition | EGF like domain multiple 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:15:00 | Thalidomide targets EGFL6 to inhibit EGFL6/PAX6 axis-driven angiogenesis in small bowel vascular malformation. | 32008086 |
| 2019-11-30 11:58:00 | It is an oncogene in CRC oncogenesis and development. | 30395690 |
| 2019-11-16 13:09:00 | In summary, we provided evidence that EGFL6 was highly expressed in nasopharyngeal carcinoma (NPC), and was associated with migration and growth of NPC cells. | 30444069 |
| 2019-11-09 11:25:00 | Results showed that EGFL6 may play an important role in the adenomacarcinoma process, and high expression predicted poor survival in colorectal cancer (CRC) patients. These findings provide evidence for EGFL6 is a novel inducer of proliferation in CRC, partially through the activation of beta-catenin via the WNT pathway. As a secreted protein, EGFL6 induces its function via secreted proteins targeting CRC cells. | 30693973 |
| 2019-10-05 10:41:00 | High EGFL6 expression may serve as a marker for poor prognosis of lung adenocarcinoma, especially in younger patients. | 29934389 |
| Type | IDs |
|---|---|
| Synonymous | MAEG, W80 |
| Gene |
UniProtKB-ID:
EGFL6_HUMAN
UniprotKB:
Q8IUX8
UniParc:
UPI000004A3C5,
UPI0000034CAE
EMBL:
AL117610,
AK075214,
AY358333,
CH471074,
AF186084,
AJ245671,
AK315018,
BC038587,
AF193055
Ensembl:
ENSG00000198759
KO:
hsa:25975
|
| Nucleutide sequences |
EMBL-CDS:
EAW98822.1,
CAB56014.2,
AAQ88699.1,
AAF27812.1,
AAG22483.1,
BAC11477.1,
AAH38587.1,
BAG37508.1,
CAB92132.1
Gene_ORFName:
UNQ281/PRO320,
PP648
Ensembl_TRS:
ENST00000361306,
ENST00000380602
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000369976,
ENSP00000355126
RefSeq:
NP_001161362.1,
NP_056322.2
|
| Others |
UniRef100:
UniRef100_Q8IUX8
UniRef90:
UniRef90_Q8IUX8
UniRef50:
UniRef50_Q9JJZ5
UniGene:
Hs.12844
CCDS:
CCDS55370.1,
CCDS14155.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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