| Type | Description |
|---|---|
| Definition | adhesion G protein-coupled receptor A2 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 11:35:00 | Serum TEM5 and TEM7 concentrations correlate with clinicopathologic features and poor prognosis of colorectal cancer patients | 31352222 |
| 2020-02-15 12:08:00 | Increases and decreases in GPR124 expression in glioblastoma cells reduce cell proliferation by differentially altering the duration mitotic progression. GPR124 interacts with ch-TOG, a known regulator of both microtubule (MT)-plus-end assembly and mitotic progression. Changes in GPR124 expression and ch-TOG similarly affect MT assembly. | 31058365 |
| 2017-08-12 12:07:00 | Data suggest that GPR124 promotes cell adhesion via interaction with Elmo1-Dock180 and intersectin 1/2; this constitutes a previously unrecognized heteromeric complex that is putatively involved in GPR124-dependent adhesive/angiogenic responses in vascular endothelial cells. (GPR124 = G-protein coupled receptor 124; Elmo1 = ELMO domain-containing protein 1; Dock180 = dedicator of cytokinesis protein 1 180 kDa) | 28600358 |
| 2014-06-14 11:56:00 | Observed an inverse correlation between the expression of miR-138-5p and GPR124 in lung adenocarcinoma specimens. Knockdown of GPR124 mimicked the effects of miR-138-5p on the sensitivity to gefitinib. | 24582749 |
| 2012-03-17 10:31:00 | Thrombin-induced shedding of tumour endothelial marker 5 and exposure of its RGD motif are regulated by cell-surface protein disulfide-isomerase. | 22013897 |
| Type | IDs |
|---|---|
| Synonymous | GPR124, TEM5 |
| Gene |
UniProtKB-ID:
AGRA2_HUMAN,
Q6YN44_HUMAN,
D3DSW5_HUMAN
UniprotKB:
Q96PE1,
Q6YN44,
D3DSW5
UniParc:
UPI00004AE50D,
UPI0000EE4D56,
UPI0000EE4D55,
UPI0000071D22,
UPI0000351988
EMBL:
AK074099,
AF378755,
AY090637,
AY181242,
AK027296,
AL110244,
AB040964,
CH471080,
AL832524,
BC146774,
AC138356
Ensembl:
ENSG00000020181
KO:
hsa:25960
|
| Nucleutide sequences |
EMBL-CDS:
AAO27354.1,
BAB84925.2,
CAD38629.1,
CAB53694.1,
BAA96055.2,
AAI46775.1,
EAW63356.1,
AAL11992.1,
BAB55022.1,
EAW63355.1,
AAM09084.1,
EAW63359.1,
EAW63354.1
Gene_ORFName:
hCG_23113
Ensembl_TRS:
ENST00000315215,
ENST00000412232
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000406367,
ENSP00000323508
RefSeq:
XP_011542785.1,
NP_116166.9,
XP_011542783.1,
XP_011542784.1
|
| Others |
UniRef100:
UniRef100_Q96PE1,
UniRef100_D3DSW5,
UniRef100_Q6YN44
UniRef90:
UniRef90_D3DSW5,
UniRef90_Q96PE1,
UniRef90_Q6YN44
UniRef50:
UniRef50_Q6YN44,
UniRef50_Q96PE1,
UniRef50_Q96PE1-2
UniGene:
Hs.274136
CCDS:
CCDS6097.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员