| Type | Description |
|---|---|
| Definition | RWD domain containing 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:37:00 | The results show RSUME involvement in von Hippel-Lindau mutants deregulation that leads to the angiogenic phenotype of renal cell carcinoma tumors. | 30890701 |
| 2019-04-13 12:20:00 | We found that overexpression in pituitary tumor cells is explained by its protein stabilization, is regulated by RSUME and accounts for duanyu1547G tumor abundance and pathogenic action. There is no evidence so far that this mechanism operates in normal cells. This finding puts in a central role the protein stabilization-overexpression of proto-oncogenes as major regulators of cellular dysfunction. | 29622689 |
| 2018-08-25 11:25:00 | miR-375 was downregulated in human gliomas and overexpression of miR-375 caused downregulation of RWDD3 in glioma cells as well as inhibited their motility. Thus, these findings suggest that RWDD3 and miR-375 may function as therapeutic biomarkers for glioma patients | 29436665 |
| 2018-02-24 11:45:00 | RSUME has a role in tumorigenesis and metastasis of pancreatic neuroendocrine tumors | 27506944 |
| 2017-02-04 11:10:00 | RSUME affects post-transcriptional expression of HIF-1a by regulating VEGF-A secretion and pituitary adenoma cells invasiveness. | 27989771 |
| Type | IDs |
|---|---|
| Synonymous | RSUME |
| Gene |
UniProtKB-ID:
RWDD3_HUMAN,
D3DT49_HUMAN
UniprotKB:
Q9Y3V2,
D3DT49
UniParc:
UPI000059D012,
UPI0000EE5DA3,
UPI0004EFFC6A,
UPI000013D481,
UPI0000E056CB
EMBL:
BC125142,
BC010936,
AK292665,
AL050062,
CR533493,
AK292699,
CH471097,
AC092802
Ensembl:
ENSG00000122481
KO:
hsa:25950
|
| Nucleutide sequences |
EMBL-CDS:
BAF85354.1,
AAI25143.1,
CAG38524.1,
BAF85388.1,
CAB43254.2,
EAW73019.1,
EAW73022.1
Gene_ORFName:
hCG_2028355
Ensembl_TRS:
ENST00000263893,
ENST00000370202
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000359221,
ENSP00000263893
RefSeq:
NP_056300.3,
NP_001265177.2,
NP_001121614.2,
NP_001186611.2,
NP_001265176.2
|
| Others |
UniRef100:
UniRef100_D3DT49,
UniRef100_Q9Y3V2
UniRef90:
UniRef90_Q9Y3V2,
UniRef90_A0A2I2ZN15
UniRef50:
UniRef50_Q9Y3V2-4,
UniRef50_Q9Y3V2
UniGene:
Hs.483512,
Hs.709591
CCDS:
CCDS41357.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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