| Type | Description |
|---|---|
| Definition | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:12:00 | SAMHD1-mediated dNTP degradation is required for efficient DNA repair during antibody class switch recombination. | 32511795 |
| 2021-04-13 10:08:00 | TLR4-Mediated Pathway Triggers Interferon-Independent G0 Arrest and Antiviral SAMHD1 Activity in Macrophages. | 32209460 |
| 2021-03-27 14:40:00 | SAMHD1 restrains aberrant nucleotide insertions at repair junctions generated by DNA end joining. | 33591315 |
| 2021-03-20 13:30:00 | SAMHD1 expression is associated with low immune activation but not correlated with HIV1 DNA levels in CD4+ T cells of patients with HIV1. | 32468062 |
| 2021-01-23 13:01:00 | Generation of three induced pluripotent cell lines (iPSCs) from an Aicardi-Goutieres syndrome (AGS) patient harboring a deletion in the genomic locus of the sterile alpha motif and HD domain containing protein 1 (SAMHD1). | 32062129 |
| Type | IDs |
|---|---|
| Synonymous | CHBL2, DCIP, HDDC1, MOP-5, SBBI88, hSAMHD1 |
| Gene |
UniProtKB-ID:
SAMH1_HUMAN,
Q59H15_HUMAN
UniprotKB:
Q9Y3Z3,
Q59H15
UniParc:
UPI00004F6AEC,
UPI00033362AD,
UPI0000035DA0,
UPI000333629C
EMBL:
AL079335,
AB013847,
AL365505,
BC036450,
AK304187,
AK027811,
CH471077,
AF228421,
AL050267,
AB208944
Ensembl:
ENSG00000101347
KO:
hsa:25939
|
| Nucleutide sequences |
EMBL-CDS:
BAB55386.1,
AAF32407.1,
EAW76091.1,
AAH36450.1,
BAG65067.1,
EAW76090.1,
BAB18916.1,
CAB43368.1,
BAD92181.1
Ensembl_TRS:
ENST00000262878,
ENST00000646673,
ENST00000646869,
ENST00000646066
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000493536,
ENSP00000495667,
ENSP00000262878,
ENSP00000495432
RefSeq:
NP_056289.2,
NP_001350658.1,
NP_001350662.1
|
| Others |
UniRef100:
UniRef100_Q9Y3Z3,
UniRef100_Q59H15
UniRef90:
UniRef90_Q9Y3Z3,
UniRef90_Q59H15
UniRef50:
UniRef50_Q9Y3Z3,
UniRef50_Q59H15
UniGene:
Hs.580681
CCDS:
CCDS13288.1,
CCDS86953.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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