| Type | Description |
|---|---|
| Definition | liver-expressed antimicrobial peptide 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:25:00 | Growth hormone secretagogue receptor signalling affects high-fat intake independently of plasma levels of ghrelin and LEAP2, in a 4-day binge eating model. | 31469195 |
| 2020-05-16 11:58:00 | plasma LEAP2/acyl-ghrelin molar ratio may be a key determinant modulating acyl-ghrelin activity in response to body mass, feeding status, and blood glucose. | 31424424 |
| 2019-06-08 11:32:00 | liver-expressed antimicrobial peptide 2 (LEAP2) is an endogenous antagonist of GHSR. | 29233536 |
| Type | IDs |
|---|---|
| Synonymous | leap-2 |
| Gene |
UniProtKB-ID:
LEAP2_MOUSE
UniprotKB:
Q91V13
UniParc:
UPI0000023E2C
EMBL:
AJ409055,
AJ409063,
BC089593
Ensembl:
ENSMUSG00000036216
KO:
mmu:259301
|
| Nucleutide sequences |
EMBL-CDS:
CAC51519.1,
CAC51472.1,
AAH89593.1
Ensembl_TRS:
ENSMUST00000036045
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000044166
RefSeq:
NP_694709.1
|
| Others |
UniRef100:
UniRef100_Q91V13
UniRef90:
UniRef90_Q91V13
UniRef50:
UniRef50_Q969E1
UniGene:
Mm.24283
CCDS:
CCDS36150.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31469195 |
J Neuroendocrinol MarÃa Paula Cornejo , Daniel Castrogiovanni , Helgi B Schiöth , Mirta Reynaldo , Jacky Marie , Jean-Alain Fehrentz , Mario Perello |
2019-10-01 | - |
| 31424424 |
LEAP2 changes with body mass and food intake in humans and mice. J Clin Invest Bharath K Mani , Nancy Puzziferri , Zhenyan He , Juan A Rodriguez , Sherri Osborne-Lawrence , Nathan P Metzger , Navpreet Chhina , Bruce Gaylinn , Michael O Thorner , E Louise Thomas , Jimmy D Bell , Kevin W Williams , Anthony P Goldstone , Jeffrey M Zigman |
2019-09-03 | - |
| 29233536 |
LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor. Cell Metab. Xuecai Ge , Hong Yang , Maria A Bednarek , Hadas Galon-Tilleman , Peirong Chen , Michael Chen , Joshua S Lichtman , Yan Wang , Olivier Dalmas , Yiyuan Yin , Hui Tian , Lutz Jermutus , Joseph Grimsby , Cristina M Rondinone , Anish Konkar , Daniel D Kaplan |
2018-02-06 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 15131800 |
Multigenic control of hepatic iron loading in a murine model of hemochromatosis. Gastroenterology Mounia Bensaid , Séverine Fruchon , Christine Mazères , Seiamak Bahram , Marie-Paule Roth , Hélène Coppin |
2004-05-01 | - |
| 14610273 |
Proc. Natl. Acad. Sci. U.S.A. Brian P Zambrowicz , Alejandro Abuin , Ramiro Ramirez-Solis , Lizabeth J Richter , James Piggott , Hector BeltrandelRio , Eric C Buxton , Joel Edwards , Rick A Finch , Carl J Friddle , Anupma Gupta , Gwenn Hansen , Yi Hu , Wenhu Huang , Crystal Jaing , Billie Wayne Key , Peter Kipp , Buckley Kohlhauff , Zhi-Qing Ma , Diane Markesich , Robert Payne , David G Potter , Ny Qian , Joseph Shaw , Jeff Schrick , Zheng-Zheng Shi , Mary Jean Sparks , Isaac Van Sligtenhorst , Peter Vogel , Wade Walke , Nianhua Xu , Qichao Zhu , Christophe Person , Arthur T Sands |
2003-11-25 |
Gm14018,
Notumos,
Ldlrap1,
Mdn1,
Gm11335,
Rps12-ps4,
Gm17762,
Umad1,
BC028777,
Gm13999,
Gm9744,
Gm11696,
Dnajc3,
Rsph3b,
D030047H15Rik,
Gm10685,
Gm10876,
Gm10433,
Gm10706,
Gm15441,
Gm10787,
Apela,
Gm10640,
Dnmt3aos,
Gm10822,
Gm10687,
Gm10658,
Gm11744,
Gm10848,
Gm10535,
F420014N23Rik,
Gm16287,
Gm10463,
Fmr1os,
Gm12298,
Tmem51os1,
Gm14488,
Gm15401,
Gm10209,
Gm1976,
Gm1974,
Gm1998,
Gm13552,
Gm10031,
Gm20796,
Gm11496,
Gm2022,
Gm2050,
Gm2058,
Gm13580,
Gm2085,
Gm2087,
Gm2137,
Rps16-ps2,
Gm2183,
Gm2225,
B230206L02Rik,
Gm15706,
Gm2294,
Gm2295,
Gm2297,
Tbx3os1,
Gm2312,
Gm2315,
Gm2329,
Gm10320,
Lncenc1,
Gm2379,
Gm2381,
Gm12168,
Gm2419,
Hrct1,
Gm2428,
D5Ertd605e,
Gm2434,
Gm16020,
Gm2443,
Gm2450,
Gm2456,
Snhg12,
Gm2479,
Gm13022,
Gm2494,
Gm12184,
Gm2529,
Gm2530,
Gm2582,
Gm12193,
Gm2603,
Gm2650,
Rsf1os2,
Gm2667,
Gm13182,
Gm2672,
Gm2679,
Gm1862,
Gm2685,
Gm2695,
Gm2698
|
| 12493837 |
Isolation and biochemical characterization of LEAP-2, a novel blood peptide expressed in the liver. Protein Sci. Alexander Krause , Rannar Sillard , Burkhard Kleemeier , Enno Klüver , Erik Maronde , José Ramon Conejo-GarcÃa , Wolf Georg Forssmann , Peter Schulz-Knappe , Michael C Nehls , Frank Wattler , Sigrid Wattler , Knut Adermann |
2003-01-01 |
Leap2,
Leap2,
LEAP2,
LEAP2,
LEAP2,
LEAP2
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员