| Type | Description |
|---|---|
| Definition | sclerostin domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:45:00 | Characterization of the different oligomeric states of the DAN family antagonists SOSTDC1 and SOST. | 32779697 |
| 2020-10-31 13:14:00 | Downregulation of Sostdc1 in Testicular Sertoli Cells is Prerequisite for Onset of Robust Spermatogenesis at Puberty. | 31391487 |
| 2020-08-01 15:10:00 | Study revealed upregulation of ADAMTS8 and downregulation of FRAS1 and SOSTDC1 in primary fibroblasts from linear morphoea (LM) lesions. SOSTDC1 knock-down recapitulated the reduced TGF -beta1 responsiveness and LM fibroblast migration, while overexpression of ADAMTS 8 induced myofibroblast markers. | 30367460 |
| 2020-02-15 13:00:00 | As rat Sostdc1 and human SOSTDC1 are dual antagonists of the Wnt/beta-catenin and BMP signaling pathways, these results underscore the potential crucial roles of these pathways and their antagonists, such as Sostdc1 and SOSTDC1, in developing and adult mammalian normal eyes as well as in syndromic and nonsyndromic congenital eye diseases. | 31529323 |
| 2019-11-23 11:58:00 | Lack of association between SOSTDC1 gene polymorphisms and mesiodens | 31133012 |
| Type | IDs |
|---|---|
| Synonymous | CDA019, DAND7, ECTODIN, USAG1 |
| Gene |
UniProtKB-ID:
SOSD1_HUMAN,
A4D125_HUMAN
UniprotKB:
Q6X4U4,
A4D125
UniParc:
UPI000004BA5E,
UPI000020EB66
EMBL:
AK093408,
AL050024,
BC008484,
AY255634,
AC079155,
AB059270,
CH471073,
AK315682,
AF361494,
AC005014,
CH236948
Ensembl:
ENSG00000171243
KO:
hsa:25928
|
| Nucleutide sequences |
EMBL-CDS:
CAB43243.2,
AAH08484.1,
BAC20331.1,
AAQ96855.1,
BAG52710.1,
AAL57219.1,
AAQ83296.1,
BAG38047.1,
EAL24287.1,
EAW93669.1
Gene_ORFName:
CDA019,
tcag7.902,
hCG_19295
Ensembl_TRS:
ENST00000307068,
ENST00000396652
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000304930,
ENSP00000379889
RefSeq:
NP_056279.1
|
| Others |
UniRef100:
UniRef100_Q6X4U4
UniRef90:
UniRef90_Q6X4U4
UniRef50:
UniRef50_Q6X4U4
UniGene:
Hs.648106
CCDS:
CCDS5360.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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