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259266 ASPM

259266

ASPM

abnormal spindle microtubule assembly

protein-coding

Homo sapiens

基因描述

Type Description
Definition abnormal spindle microtubule assembly

研究结论

Date Results Publications
2021-04-17 13:16:00 CCNB2, TOP2A, and ASPM Reflect the Prognosis of Hepatocellular Carcinoma, as Determined by Weighted Gene Coexpression Network Analysis. 32685486
2021-01-09 13:28:00 Evaluation of ASPM and TEF Gene Expressions as Potential Biomarkers for Bladder Cancer. 32274607
2020-06-06 10:28:00 Expression of ASPM in Lung Adenocarcinoma and Its Relationship with Development and Prognosis 31948535
2020-04-25 10:55:00 In pancreatic tumors, ASPM-isoform I is cytoplasmic-localized and regulates Wnt signaling and tumor stem cells through its antagonism with the E3 ubiquitin ligase of Dvl-2, whereas ASPM-isoform II is mainly nuclear-localized and regulates essential housekeeping functions of tumor cells. 31465125
2019-09-07 11:50:00 in three colorectal cancers and two gastric cancers, observed ASPM somatic mutations, which consisted of a frameshift mutation by deletion of one base (c.5149delA (p. Ile1717fsX1)) or another frameshift mutation by duplication of one base (c.5149delA (p. Ile1717AsnfsX24)) in the A7 repeat 27571986

名称对应

Type IDs
Synonymous ASP, Calmbp1, MCPH5
Gene
UniProtKB-ID: ASPM_HUMAN, B3KWI2_HUMAN
UniprotKB: Q8IZT6, B3KWI2
UniParc: UPI00004A23EA, UPI00003B2583, UPI0000458904
EMBL: AY099890, BC015396, AK125107, AF509326, AY101201, AY367065, AY099893, CH471067, AL353809, AY099892, AK001411, BC034607, AY971956, AY099891
Ensembl: ENSG00000066279
KO: hsa:259266
Nucleutide sequences
EMBL-CDS: AAM44119.1, AAH15396.1, AAM44121.1, AAH34607.1, AAM44120.1, AAM48745.1, AAR12641.1, BAA91676.1, AAY46814.1, EAW91274.1, AAN40011.1, AAM44122.1, BAG54144.1
Ensembl_TRS: ENST00000294732, ENST00000367409
Protein sequencees
Ensembl_PRO: ENSP00000356379, ENSP00000294732
RefSeq: NP_060606.3, NP_001193775.1
Others
UniRef100: UniRef100_Q8IZT6, UniRef100_B3KWI2
UniRef90: UniRef90_Q8IZT6, UniRef90_B3KWI2
UniRef50: UniRef50_Q8IZT6, UniRef50_B3KWI2
UniGene: Hs.121028
CCDS: CCDS1389.1, CCDS55672.1

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