| Type | Description |
|---|---|
| Definition | purinergic receptor P2X, ligand-gated ion channel, 4a |
| Date | Results | Publications |
|---|---|---|
| 2016-12-17 11:18:00 | Our NMR analyses also revealed that the transmembrane region adopts the open conformation in the state bound to the inhibitor trinitrophenyl-ATP, and thus the antagonism is due to the closure of ion pathways, except for the pore in the transmembrane region: i.e., the lateral cation access in the extracellular region. | 27071117 |
| 2015-01-17 13:12:00 | ATP-recognition of P2X4 receptors | 24878662 |
| 2013-12-14 12:02:00 | a property that is essential for purinergic sensory signaling. Apo and ATP-bound X-ray structures of the detergent-solubilized zebrafish P2X4 receptor provide a blueprint for receptor mechanisms | 24082111 |
| 2012-06-30 11:50:00 | crystal structure of the zebrafish P2X4 receptor in complex with ATP and a new structure of the apo receptor | 22535247 |
| 2012-05-12 10:04:00 | These computational studies produced the first complete model, supported by experimental data, for how ATP binding triggers activation of a P2X receptor. | 22378652 |
| Type | IDs |
|---|---|
| Synonymous | p2rx4, p2x4, wu:fi03f02 |
| Gene |
UniProtKB-ID:
Q98TZ0_DANRE
UniprotKB:
Q98TZ0
UniParc:
UPI00000FB305
EMBL:
AF317643
KO:
dre:259258
|
| Nucleutide sequences |
EMBL-CDS:
AAK00945.1
|
| Protein sequencees |
RefSeq:
XP_021324424.1,
NP_705939.1,
XP_009293554.1
|
| Others |
UniRef100:
UniRef100_Q98TZ0
UniRef90:
UniRef90_Q6NYR1
UniRef50:
UniRef50_Q99571
UniGene:
Dr.80370
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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