| Type | Description |
|---|---|
| Definition | zinc finger protein 521 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:45:00 | The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway. | 31558698 |
| 2020-02-29 11:32:00 | Zinc finger protein 521 can arrest the apoptosis and enhance the proliferation, migration, and invasion of gastric cancer cells via regulating microRNA-204-5p. Our study may provide novel clues for the treatment of patients with gastric cancer. | 31526099 |
| 2019-08-10 11:09:00 | these results confirm a role for ZNF521 as a key negative regulator of adipocyte differentiation of Adipose-Derived | 29938352 |
| 2019-07-06 13:00:00 | Examination of early adipogenic signals in subcutaneous adipose tissue identifies ZNF521 as a key regulator of maintaining human adipose stromal vascular fraction cells proliferative and uncommitted. Silencing ZNF521 increases BMP4 and nuclear import of the adipogenic marker and PPARgamma transcriptional activator ZNF423. | 31227697 |
| 2019-03-30 10:08:00 | Together with our previous findings, these results show that ZNF521 inhibits both adipocytic and osteoblastic maturation in Human adipose-derived stem cells (hADSCs) and suggest that its expression may contribute to maintaining the immature properties of hADSCs | 30567301 |
| Type | IDs |
|---|---|
| Synonymous | EHZF, Evi3 |
| Gene |
UniProtKB-ID:
ZN521_HUMAN,
J3KTI4_HUMAN,
Q8IYZ2_HUMAN
UniprotKB:
Q96K83,
J3KTI4,
Q8IYZ2
UniParc:
UPI000006F982,
UPI00001BDAE5,
UPI0001EEB7CD
EMBL:
CH471088,
AK074046,
BC113648,
AF141339,
BC113622,
KF456355,
DQ845345,
BC032869,
AL117615,
EF445043,
AK027354,
AC110603,
AC104961,
AK021452,
KF456358,
AC105114,
AJ518106
Ensembl:
ENSG00000198795
KO:
hsa:25925
|
| Nucleutide sequences |
EMBL-CDS:
BAB13829.1,
EAX01201.1,
ACA06095.1,
AAG49442.1,
CAD57322.1,
CAB56016.1,
ABI33104.1,
BAB84872.1,
BAB55056.1,
AAI13649.1,
AAI13623.1,
AAH32869.2
Ensembl_TRS:
ENST00000361524,
ENST00000538137,
ENST00000584787
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000440768,
ENSP00000354794,
ENSP00000463000
RefSeq:
XP_016881186.1,
XP_011524211.1,
XP_011524213.1,
XP_016881187.1,
NP_001295154.1,
XP_024306909.1,
XP_011524212.1,
NP_056276.1,
XP_024306910.1
|
| Others |
UniRef100:
UniRef100_Q8IYZ2,
UniRef100_Q96K83
UniRef90:
UniRef90_Q96K83
UniRef50:
UniRef50_Q96K83
UniGene:
Hs.116935
CCDS:
CCDS32806.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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