| Type | Description |
|---|---|
| Definition | MAS related GPR family member X1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:34:00 | BAM8-22 and its receptor MRGPRX1 may attribute to cholestatic pruritus. | 31350433 |
| 2020-08-12 12:52:00 | Our findings established a novel function for Mrgprc11 in the gut nociceptive innervation | 31119828 |
| 2019-03-09 10:19:00 | Study reports that a cysteine protease mucunain, active component of cowhage (itch-inducing spicules or trichomes that cover the seedpods of the tropical plant Mucuna pruriens) that is routinely used in human studies of histamine-independent itch, activates human MRGPRX1 and MRGPRX2 receptors and induces degranulation of human mast cells. | 28988117 |
| 2018-04-14 10:25:00 | MRGPRX1 is a promising target for pain inhibition, a humanized mouse model expressing this receptor has been described. | 28223516 |
| 2017-10-28 11:58:00 | Der p1 also induced the release of IL-6 from heterologous cells expressing MRGPRX1. In summary, activation of Mrgprs by the allergen Der p1 may contribute to inflammation. | 28768771 |
| Type | IDs |
|---|---|
| Synonymous | GPCR, MGRG2, MRGX1, SNSR4 |
| Gene |
UniProtKB-ID:
MRGX1_HUMAN,
W8W3P5_HUMAN
UniprotKB:
Q96LB2,
W8W3P5
UniParc:
UPI000003BCCF
EMBL:
AY042213,
AB083628,
AF474990,
AC023078,
CH471064,
AF474989,
HG426070,
AB065846,
BC096835
Ensembl:
ENSG00000170255
KO:
hsa:259249
|
| Nucleutide sequences |
EMBL-CDS:
AAH96835.1,
AAL86880.2,
BAB89341.1,
BAC06064.1,
AAK91804.1,
AAL86881.1,
CDG86188.1,
EAW68360.1
Gene_ORFName:
hCG_1991280
Ensembl_TRS:
ENST00000302797
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000305766
RefSeq:
NP_671732.3
|
| Others |
UniRef100:
UniRef100_Q96LB2
UniRef90:
UniRef90_Q96LB2
UniRef50:
UniRef50_Q96LB2
UniGene:
Hs.711459
CCDS:
CCDS7846.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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