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25920 NELFB

25920

NELFB

negative elongation factor complex member B

protein-coding

Homo sapiens

基因描述

Type Description
Definition negative elongation factor complex member B

研究结论

Date Results Publications
2018-10-27 10:52:00 BRCA1 Interacting Protein COBRA1 Facilitates Adaptation to Castrate-Resistant Growth Conditions. 30036938
2017-11-25 15:03:00 A positively charged face of NELF-AC is involved in RNA binding, whereas the opposite face of the NELF-AC subcomplex binds NELF-B. NELF-B is predicted to form a HEAT repeat fold, also binds RNA in vivo, and anchors the subunit NELF-E, which is confirmed to bind RNA in vivo. 27282391
2017-07-15 11:22:00 High COBRA1 expression is associated with hepatocellular carcinoma. 28112367
2016-04-23 11:37:00 both human and mouse NELF-B proteins are translated from a non-AUG codon upstream of the annotated AUG. 26010750
2014-02-08 10:47:00 These studies allow us to position the actions of two new modulators of GR-regulated transactivation, NELF-A and NELF-B, relative to other factors in the overall gene induction sequence. 24097989

名称对应

Type IDs
Synonymous COBRA1, NELF-B
Gene
UniProtKB-ID: NELFB_HUMAN
UniprotKB: Q8WX92
UniParc: UPI0006573AD6, UPI0000070699
EMBL: AF464935, AK091056, AB033008, AL050280, AK022651, BX255925, BC011892
Ensembl: ENSG00000188986
KO: hsa:25920
Nucleutide sequences
EMBL-CDS: BAB14157.1, AAH11892.1, CAB43381.3, AAL69965.1, BAG52272.1, BAA86496.1
Ensembl_TRS: ENST00000634710
Protein sequencees
Ensembl_PRO: ENSP00000489248
RefSeq: NP_056271.3
Others
UniRef100: UniRef100_Q8WX92
UniRef90: UniRef90_Q8WX92
UniRef50: UniRef50_Q8WX92
UniGene: Hs.521809
CCDS: CCDS7040.2

全选

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研究热度

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