| Type | Description |
|---|---|
| Definition | transmembrane protein 158 (gene/pseudogene) |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:25:00 | Silencing of TMEM158 Inhibits Tumorigenesis and Multidrug Resistance in Colorectal Cancer. | 31389251 |
| 2020-12-19 13:37:00 | TMEM158 promotes pancreatic cancer aggressiveness by activation of TGFbeta1 and PI3K/AKT signaling pathway. | 31531884 |
| 2010-01-21 00:00:00 | RIS1 exhibits frameshift mutations in high-frequency microsatellite instability tumors, and its alteration is correlated with mutations in two target genes BAX and TGFBR2, linking it to the mutator pathway in colorectal carcinogenesis. | 16737913 |
| 2010-01-21 00:00:00 | Suggested role of Ris-1 as tumor suppressor gene is not evident, at least in breast cancer. | 16280139 |
| Type | IDs |
|---|---|
| Synonymous | BBP, RIS1, p40BBP |
| Gene |
UniProtKB-ID:
TM158_HUMAN
UniprotKB:
Q8WZ71
UniParc:
UPI00001CE033,
UPI0000E5DD5E
EMBL:
AB078417,
AF438313,
AL080235,
BC057390,
AC010170
Ensembl:
ENSG00000249992
KO:
hsa:25907
|
| Nucleutide sequences |
EMBL-CDS:
CAB45781.1,
AAH57390.1,
AAL30845.1,
BAC05687.1
Ensembl_TRS:
ENST00000503771
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000422431
RefSeq:
NP_056259.2
|
| Others |
UniRef100:
UniRef100_Q8WZ71
UniRef90:
UniRef90_Q8WZ71
UniRef50:
UniRef50_Q8WZ71
UniGene:
Hs.740403
CCDS:
CCDS54573.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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