| Type | Description |
|---|---|
| Definition | anaphase promoting complex subunit 15 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-27 11:43:00 | cryo-EM structure of an APC/C-Cdh1 complex with Apc1(WD40) deleted showed that the mutant APC/C is locked into an inactive conformation in which the UbcH10-binding site of the catalytic module is inaccessible. Additionally, an EM density for Apc15 is not visible | 27601667 |
| 2013-06-07 16:38:00 | Anaphase promoting complex subunit 15(APC15) mediates the constant turnover of CDC20 and mitotic checkpoint protein complexes, allowing the spindle checkpoint assembly to respond to the attachment state of kinetochores. | 21926987 |
| 2013-01-26 10:21:00 | APC15 is required for anaphase-promoting complex/cyclosome-bound mitotic checkpoint complex-dependent CDC20 autoubiquitylation and degradation and for timely anaphase initiation. | 23007861 |
| Type | IDs |
|---|---|
| Synonymous | APC15, C11orf51, HSPC020 |
| Gene |
UniProtKB-ID:
APC15_HUMAN,
A0A024R5G0_HUMAN,
G5EA39_HUMAN
UniprotKB:
P60006,
A0A024R5G0,
G5EA39
UniParc:
UPI00001FAE94,
UPI0000EE46B1,
UPI000002356F
EMBL:
BC005156,
AL080071,
CH471076,
BC005393,
AF077206,
AK222622,
AP000812
Ensembl:
ENSG00000110200
KO:
hsa:25906
|
| Nucleutide sequences |
EMBL-CDS:
AAD27001.1,
CAB45698.1,
EAW74842.1,
AAH05393.1,
AAH05156.1,
EAW74838.1,
EAW74841.1,
EAW74840.1
Gene_ORFName:
HSPC020,
hCG_23235,
hCG_23235
Ensembl_TRS:
ENST00000535234,
ENST00000543587,
ENST00000535503,
ENST00000545944,
ENST00000227618,
ENST00000542531,
ENST00000545680,
ENST00000538919,
ENST00000538393,
ENST00000543050
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000440002,
ENSP00000446412,
ENSP00000227618,
ENSP00000440983,
ENSP00000446383,
ENSP00000443911,
ENSP00000439403,
ENSP00000443645,
ENSP00000443383,
ENSP00000437360
RefSeq:
NP_001265421.1,
NP_001265417.1,
NP_001265420.1,
NP_001265415.1,
NP_001265422.1,
XP_016872986.1,
NP_001265419.1,
NP_054761.1,
NP_001265418.1,
NP_001265416.1,
NP_001265414.1,
NP_001265423.1,
XP_016872985.1,
NP_001317250.1
|
| Others |
UniRef100:
UniRef100_G5EA39,
UniRef100_P60006
UniRef90:
UniRef90_P60006,
UniRef90_G5EA39
UniRef50:
UniRef50_G5EA39,
UniRef50_P60006
UniGene:
Hs.38044
CCDS:
CCDS8210.1,
CCDS60880.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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