| Type | Description |
|---|---|
| Definition | polypeptide N-acetylgalactosaminyltransferase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 15:17:00 | we report the clinical, biochemical, and molecular features of seven patients from four families with GALNT2-congenital disorder of glycosylation (GALNT2-CDG), an O-linked glycosylation disorder | 32293671 |
| 2020-03-07 10:50:00 | facilitates the malignant characteristics of glioma by influencing the O-glycosylation and phosphorylation of EGFR and the subsequent downstream PI3K/Akt/mTOR axis | 31076460 |
| 2018-07-28 10:09:00 | GALNT2 rs12040273 variants might not be associated with the susceptibility of coronary artery disease or its severity in a Chinese Han population. The CC genotype could be associated with elevated serum HDL-C levels. | 29351739 |
| 2017-12-09 12:05:00 | Our results indicate that GALNT2 suppresses the malignant potential of gastric adenocarcinoma cells | 26848976 |
| 2017-08-12 10:21:00 | The crystal structure of GalNAc-T2 with the galactose derivative traps the enzyme in an inactive form; this suggests that compounds only containing the beta-phosphate could be efficient ligands for the enzyme. Computational studies with GalNAc-T2 corroborate these findings and provide further insights into the mechanism of the catalytic cycle of this family of enzymes. | 27071848 |
| Type | IDs |
|---|---|
| Synonymous | GalNAc-T2 |
| Gene |
UniProtKB-ID:
GALT2_HUMAN,
B7Z6K2_HUMAN,
A0A1L7NY50_HUMAN,
G3V1S6_HUMAN
UniprotKB:
Q10471,
B7Z6K2,
A0A1L7NY50,
G3V1S6
UniParc:
UPI0000EE5DAD,
UPI0000074053,
UPI0001915252,
UPI0001915203
EMBL:
LC043140,
FJ515852,
BC041120,
AK290048,
AK300453,
AK304029,
AL117349,
CH471098,
X85019,
AL592228,
AL136988,
AL078646
Ensembl:
ENSG00000143641
KO:
hsa:2590
|
| Nucleutide sequences |
EMBL-CDS:
BAH14094.1,
BAF82737.1,
EAW69911.1,
CAA59381.1,
ACS13744.1,
AAH41120.1,
BAH13288.1,
BAW34839.1,
EAW69910.1,
EAW69909.1
Gene_ORFName:
hCG_15927
Ensembl_TRS:
ENST00000366672
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355632
RefSeq:
XP_016856455.1,
NP_001278795.1,
XP_016856453.1,
XP_016856452.1,
XP_016856454.1,
NP_004472.1
|
| Others |
UniRef100:
UniRef100_B7Z6K2,
UniRef100_Q10471,
UniRef100_G3V1S6
UniRef90:
UniRef90_Q10471,
UniRef90_G3V1S6,
UniRef90_B7Z6K2
UniRef50:
UniRef50_D3ZFD2,
UniRef50_Q10471
UniGene:
Hs.743964
CCDS:
CCDS1582.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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