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25898 RCHY1

25898

RCHY1

ring finger and CHY zinc finger domain containing 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition ring finger and CHY zinc finger domain containing 1

研究结论

Date Results Publications
2020-07-11 10:20:00 These data provide an evidence that RCHY1 negatively regulates HDAC2. 31630802
2020-01-25 14:02:00 By forming a complex with Twist1 and the E3 ligase Pirh2, WT p53 promotes the ubiquitination and proteasomal degradation of Twist1, thus inhibiting EMT and maintaining the epithelial phenotype. The ability of p53 to induce Twist1 degradation is abrogated when p53 is mutated. 30131448
2020-01-11 12:12:00 higher expression level of Naa10 and lower expression level of Pirh2 in oral squamous cell carcinoma tissues than adjacent normal tissues; expression of Naa10p is negatively correlated with that of Pirh2 31134698
2018-07-14 11:38:00 High Pirh2 expression was positively correlated with high tumor grade in brain glioma specimens. 28258514
2018-03-31 10:04:00 Data indicate cellular E3 ubiquitin ligase ring-finger and CHY zinc-finger domain-containing 1 (RCHY1) as an interacting partner of the viral SARS-unique domain (SUD) and papain-like protease (PL(pro)), and, as a consequence, the involvement of cellular p53 as antagonist of coronaviral replication. 27519799

名称对应

Type IDs
Synonymous ARNIP, CHIMP, PIRH2, PRO1996, RNF199, ZCHY, ZNF363
Gene
UniProtKB-ID: ZN363_HUMAN
UniprotKB: Q96PM5
UniParc: UPI0001CDD7BD, UPI0001D3B498, UPI0000E203AB, UPI0000413009, UPI000013C366, UPI00004DF233, UPI000041300A, UPI000069243E
EMBL: GQ250945, AF255666, AK091501, CH471057, GQ250946, AY888047, BC047393, AF247041, GQ250944, AC096759, AB209072, GU937000, AF305424
Ensembl: ENSG00000163743
KO: hsa:25898
Nucleutide sequences
EMBL-CDS: BAD92309.1, AAL09356.1, ACT35533.1, AAL76101.1, AAH47393.1, ADD21555.1, AAX78233.1, ACT35532.1, AAK96896.1, BAG52375.1, ACT35531.1, EAX05725.1
Ensembl_TRS: ENST00000324439, ENST00000512706, ENST00000505105, ENST00000507014, ENST00000513257, ENST00000380840
Protein sequencees
Ensembl_PRO: ENSP00000424631, ENSP00000421084, ENSP00000321239, ENSP00000424472, ENSP00000370220, ENSP00000423976
RefSeq: XP_024309752.1, NP_001265467.1, NP_001265468.1, NP_001265466.1, NP_001374066.1, NP_001374065.1, NP_001265465.1, NP_001009922.1, NP_056251.2
Others
UniRef100: UniRef100_Q96PM5
UniRef90: UniRef90_Q96PM5
UniRef50: UniRef50_Q96PM5
UniGene: Hs.48297
CCDS: CCDS63990.1, CCDS3567.1, CCDS63991.1, CCDS34012.1, CCDS63992.1

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