| Type | Description |
|---|---|
| Definition | tripartite motif containing 58 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:26:00 | TRIM58 Interacts with Pyruvate Kinase M2 to Inhibit Tumorigenicity in Human Osteosarcoma Cells. | 32219144 |
| 2020-05-16 11:54:00 | Identify TRIM58 as a novel negative mediator of innate immune control and mucosal homeostasis via TLR2 signaling. | 31383741 |
| 2018-11-10 11:59:00 | Low TRIM58 expression is associated with colorectal cancer cell invasion. | 29956813 |
| 2018-10-13 10:39:00 | he present study would help to elucidate the influence of TRIM58/cg26157385 methylation on lung cancer prognosis | 29749538 |
| 2018-03-10 11:53:00 | Our findings suggest that aberrant inactivation of TRIM58 consequent to CGI hypermethylation might stimulate the early carcinogenesis of LADC regardless of smoking status; furthermore, TRIM58 methylation might be a possible early diagnostic and epigenetic therapeutic target in LADC. | 27926516 |
| Type | IDs |
|---|---|
| Synonymous | BIA2 |
| Gene |
UniProtKB-ID:
TRI58_HUMAN
UniprotKB:
Q8NG06
UniParc:
UPI000020590E
EMBL:
BC074748,
AF327057
Ensembl:
ENSG00000162722
KO:
hsa:25893
|
| Nucleutide sequences |
EMBL-CDS:
AAM63958.1,
AAH74748.1
Ensembl_TRS:
ENST00000366481
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355437
RefSeq:
NP_056246.3
|
| Others |
UniRef100:
UniRef100_Q8NG06
UniRef90:
UniRef90_Q8NG06
UniRef50:
UniRef50_Q8NG06
UniGene:
Hs.269151
CCDS:
CCDS1636.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32219144 |
TRIM58 Interacts with Pyruvate Kinase M2 to Inhibit Tumorigenicity in Human Osteosarcoma Cells. Biomed Res Int Peng Yuan , Yiyi Zhou , Rui Wang , Shayang Chen , Qiqi Wang , Zhujie Xu , Yi Liu , Huilin Yang |
2020-01-01 | - |
| 31747856 |
Cancer Biol Ther Xiaowen Liu , Ziwen Long , Hong Cai , Shengjia Yu , Jianghong Wu |
2020-01-01 | - |
| 31383741 |
TRIM58 Restrains Intestinal Mucosal Inflammation by Negatively Regulating TLR2 in Myeloid Cells. J. Immunol. Annette Eyking , Frederike Ferber , Stefanie Köhler , Henning Reis , Elke Cario |
2019-09-15 | - |
| 29956813 |
Oncol. Rep. Min Liu , Xiaowen Zhang , Jian Cai , Yichen Li , Qianxin Luo , Haiyong Wu , Zihuan Yang , Lei Wang , Daici Chen |
2018-09-01 | - |
| 29749538 |
Oncol Rep Weimin Zhang , Qichen Cui , Weifeng Qu , Xiaoyun Ding , Donglin Jiang , Hongcheng Liu |
2018-07-01 | - |
| 27926516 |
Oncotarget Koichiro Kajiura , Kiyoshi Masuda , Takuya Naruto , Tomohiro Kohmoto , Miki Watabnabe , Mitsuhiro Tsuboi , Hiromitsu Takizawa , Kazuya Kondo , Akira Tangoku , Issei Imoto |
2017-01-10 | - |
| 26354767 |
Genetics Melanie L Bailey , Tejomayee Singh , Patricia Mero , Jason Moffat , Philip Hieter |
2015-11-01 |
LINC00173,
TUBA1B,
CDR2,
DLC1,
SPAG11B,
UBAC1,
SLC35A1,
COPS6,
DIDO1,
EFHC1,
TBCB,
MTFMT,
ZC3H18,
COL1A2,
COL12A1,
DNAJC21,
LETM2,
RALYL,
ZNF563,
B3GALNT2,
CYBB,
CYLD,
TMEM65,
AP2A1,
SPRED1,
MMAA,
EPOR,
FANCD2,
C6orf136,
RSBN1L,
FGA,
PUF60,
TXLNGY,
EBF3,
GAK,
TRIM58,
NECTIN3,
FAM32A,
RBMX,
GMDS,
OR51V1,
CDH19,
C5orf51,
C5orf64,
GRIK3,
GRM3,
CPSF1,
EIF4E3,
LRRTM1,
LCE1B,
ITGAV,
GAMTP1,
HERC2P2,
LPA,
MEP1A,
MOCS1,
NUDT4P1,
PALM2-AKAP2,
NDUFB9,
RERE,
TRAT1,
PHF20L1,
CDK18,
NAT8B,
CINP,
ZFR,
RAB4B,
POLR2K,
EXOSC4,
SPDL1,
SRBD1,
RFWD3,
FBXW7,
TNFRSF19,
H2AFY2,
RNPC3,
TMEM126B,
C8orf44,
PRPSAP1,
C5orf15,
PTGDS,
SENP7,
SHROOM4,
PTPRN2,
RAG1,
VPS16,
SLC17A1,
SNRNP70,
SNRPB2,
SNRPF,
SPTBN1,
SSBP1,
SUPT6H,
MED22,
BUB1B,
OSGIN2,
MPPED1,
GGCT,
NELFE
|
| 25241935 |
Trim58 degrades Dynein and regulates terminal erythropoiesis. Dev. Cell Christopher S Thom , Elizabeth A Traxler , Eugene Khandros , Jenna M Nickas , Olivia Y Zhou , Jacob E Lazarus , Ana P G Silva , Dolly Prabhu , Yu Yao , Chiaka Aribeana , Serge Y Fuchs , Joel P Mackay , Erika L F Holzbaur , Mitchell J Weiss |
2014-09-29 |
Trim58,
DYNC1H1,
DYNC1I1,
DYNC1LI2,
TRIM58,
DYNC2LI1,
UBE2D3,
TRIM63
|
| 23222517 |
Seventy-five genetic loci influencing the human red blood cell. Nature Pim van der Harst , Weihua Zhang , Irene Mateo Leach , Augusto Rendon , Niek Verweij , Joban Sehmi , Dirk S Paul , Ulrich Elling , Hooman Allayee , Xinzhong Li , Aparna Radhakrishnan , Sian-Tsung Tan , Katrin Voss , Christian X Weichenberger , Cornelis A Albers , Abtehale Al-Hussani , Folkert W Asselbergs , Marina Ciullo , Fabrice Danjou , Christian Dina , Tõnu Esko , David M Evans , Lude Franke , Martin Gögele , Jaana Hartiala , Micha Hersch , Hilma Holm , Jouke-Jan Hottenga , Stavroula Kanoni , Marcus E Kleber , Vasiliki Lagou , Claudia Langenberg , Lorna M Lopez , Leo-Pekka Lyytikäinen , Olle Melander , Federico Murgia , Ilja M Nolte , Paul F O'Reilly , Sandosh Padmanabhan , Afshin Parsa , Nicola Pirastu , Eleonora Porcu , Laura Portas , Inga Prokopenko , Janina S Ried , So-Youn Shin , Clara S Tang , Alexander Teumer , Michela Traglia , Sheila Ulivi , Harm-Jan Westra , Jian Yang , Jing Hua Zhao , Franco Anni , Abdel Abdellaoui , Antony Attwood , Beverley Balkau , Stefania Bandinelli , François Bastardot , Beben Benyamin , Bernhard O Boehm , William O Cookson , Debashish Das , Paul I W de Bakker , Rudolf A de Boer , Eco J C de Geus , Marleen H de Moor , Maria Dimitriou , Francisco S Domingues , Angela Döring , Gunnar Engström , Gudmundur Ingi Eyjolfsson , Luigi Ferrucci , Krista Fischer , Renzo Galanello , Stephen F Garner , Bernd Genser , Quince D Gibson , Giorgia Girotto , Daniel Fannar Gudbjartsson , Sarah E Harris , Anna-Liisa Hartikainen , Claire E Hastie , Bo Hedblad , Thomas Illig , Jennifer Jolley , Mika Kähönen , Ido P Kema , John P Kemp , Liming Liang , Heather Lloyd-Jones , Ruth J F Loos , Stuart Meacham , Sarah E Medland , Christa Meisinger , Yasin Memari , Evelin Mihailov , Kathy Miller , Miriam F Moffatt , Matthias Nauck , Maria Novatchkova , Teresa Nutile , Isleifur Olafsson , Pall T Onundarson , Debora Parracciani , Brenda W Penninx , Lucia Perseu , Antonio Piga , Giorgio Pistis , Anneli Pouta , Ursula Puc , Olli Raitakari , Susan M Ring , Antonietta Robino , Daniela Ruggiero , Aimo Ruokonen , Aude Saint-Pierre , Cinzia Sala , Andres Salumets , Jennifer Sambrook , Hein Schepers , Carsten Oliver Schmidt , Herman H W Silljé , Rob Sladek , Johannes H Smit , John M Starr , Jonathan Stephens , Patrick Sulem , Toshiko Tanaka , Unnur Thorsteinsdottir , Vinicius Tragante , Wiek H van Gilst , L Joost van Pelt , Dirk J van Veldhuisen , Uwe Völker , John B Whitfield , Gonneke Willemsen , Bernhard R Winkelmann , Gerald Wirnsberger , Ale Algra , Francesco Cucca , Adamo Pio d'Adamo , John Danesh , Ian J Deary , Anna F Dominiczak , Paul Elliott , Paolo Fortina , Philippe Froguel , Paolo Gasparini , Andreas Greinacher , Stanley L Hazen , Marjo-Riitta Jarvelin , Kay Tee Khaw , Terho Lehtimäki , Winfried Maerz , Nicholas G Martin , Andres Metspalu , Braxton D Mitchell , Grant W Montgomery , Carmel Moore , Gerjan Navis , Mario Pirastu , Peter P Pramstaller , Ramiro Ramirez-Solis , Eric Schadt , James Scott , Alan R Shuldiner , George Davey Smith , J Gustav Smith , Harold Snieder , Rossella Sorice , Tim D Spector , Kari Stefansson , Michael Stumvoll , W H Wilson Tang , Daniela Toniolo , Anke Tönjes , Peter M Visscher , Peter Vollenweider , Nicholas J Wareham , Bruce H R Wolffenbuttel , Dorret I Boomsma , Jacques S Beckmann , George V Dedoussis , Panos Deloukas , Manuel A Ferreira , Serena Sanna , Manuela Uda , Andrew A Hicks , Josef Martin Penninger , Christian Gieger , Jaspal S Kooner , Willem H Ouwehand , Nicole Soranzo , John C Chambers |
2012-12-20 | - |
| 22139419 |
New gene functions in megakaryopoiesis and platelet formation. Nature Christian Gieger , Aparna Radhakrishnan , Ana Cvejic , Weihong Tang , Eleonora Porcu , Giorgio Pistis , Jovana Serbanovic-Canic , Ulrich Elling , Alison H Goodall , Yann Labrune , Lorna M Lopez , Reedik Mägi , Stuart Meacham , Yukinori Okada , Nicola Pirastu , Rossella Sorice , Alexander Teumer , Katrin Voss , Weihua Zhang , Ramiro Ramirez-Solis , Joshua C Bis , David Ellinghaus , Martin Gögele , Jouke-Jan Hottenga , Claudia Langenberg , Peter Kovacs , Paul F O'Reilly , So-Youn Shin , Tõnu Esko , Jaana Hartiala , Stavroula Kanoni , Federico Murgia , Afshin Parsa , Jonathan Stephens , Pim van der Harst , C Ellen van der Schoot , Hooman Allayee , Antony Attwood , Beverley Balkau , François Bastardot , Saonli Basu , Sebastian E Baumeister , Ginevra Biino , Lorenzo Bomba , Amélie Bonnefond , François Cambien , John C Chambers , Francesco Cucca , Pio D'Adamo , Gail Davies , Rudolf A de Boer , Eco J C de Geus , Angela Döring , Paul Elliott , Jeanette Erdmann , David M Evans , Mario Falchi , Wei Feng , Aaron R Folsom , Ian H Frazer , Quince D Gibson , Nicole L Glazer , Chris Hammond , Anna-Liisa Hartikainen , Susan R Heckbert , Christian Hengstenberg , Micha Hersch , Thomas Illig , Ruth J F Loos , Jennifer Jolley , Kay Tee Khaw , Brigitte Kühnel , Marie-Christine Kyrtsonis , Vasiliki Lagou , Heather Lloyd-Jones , Thomas Lumley , Massimo Mangino , Andrea Maschio , Irene Mateo Leach , Barbara McKnight , Yasin Memari , Braxton D Mitchell , Grant W Montgomery , Yusuke Nakamura , Matthias Nauck , Gerjan Navis , Ute Nöthlings , Ilja M Nolte , David J Porteous , Anneli Pouta , Peter P Pramstaller , Janne Pullat , Susan M Ring , Jerome I Rotter , Daniela Ruggiero , Aimo Ruokonen , Cinzia Sala , Nilesh J Samani , Jennifer Sambrook , David Schlessinger , Stefan Schreiber , Heribert Schunkert , James Scott , Nicholas L Smith , Harold Snieder , John M Starr , Michael Stumvoll , Atsushi Takahashi , W H Wilson Tang , Kent Taylor , Albert Tenesa , Swee Lay Thein , Anke Tönjes , Manuela Uda , Sheila Ulivi , Dirk J van Veldhuisen , Peter M Visscher , Uwe Völker , H-Erich Wichmann , Kerri L Wiggins , Gonneke Willemsen , Tsun-Po Yang , Jing Hua Zhao , Paavo Zitting , John R Bradley , George V Dedoussis , Paolo Gasparini , Stanley L Hazen , Andres Metspalu , Mario Pirastu , Alan R Shuldiner , L Joost van Pelt , Jaap-Jan Zwaginga , Dorret I Boomsma , Ian J Deary , Andre Franke , Philippe Froguel , Santhi K Ganesh , Marjo-Riitta Jarvelin , Nicholas G Martin , Christa Meisinger , Bruce M Psaty , Timothy D Spector , Nicholas J Wareham , Jan-Willem N Akkerman , Marina Ciullo , Panos Deloukas , Andreas Greinacher , Steve Jupe , Naoyuki Kamatani , Jyoti Khadake , Jaspal S Kooner , Josef Penninger , Inga Prokopenko , Derek Stemple , Daniela Toniolo , Lorenz Wernisch , Serena Sanna , Andrew A Hicks , Augusto Rendon , Manuel A Ferreira , Willem H Ouwehand , Nicole Soranzo |
2011-11-30 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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