| Type | Description |
|---|---|
| Definition | RNA polymerase I subunit A |
| Date | Results | Publications |
|---|---|---|
| 2018-02-24 11:46:00 | Data show that BRCA1 interacts directly with the basal RNA polymerase I (Pol-I) transcription factors as well as interacting with RNA Pol-I itself. | 27589844 |
| 2017-08-12 10:06:00 | Homozygous c.2801C>T (p.(Ser934Leu)) in POLR1A was identified in two brothers with unusual neurological disease that manifested with ataxia, psychomotor retardation, cerebellar and cerebral atrophy, and leukodystrophy. | 28051070 |
| 2015-08-01 10:07:00 | Consistent with this observation, we discovered that polr1a mutant zebrafish exhibited cranioskeletal anomalies mimicking the human phenotype. polr1a loss of function led to perturbed ribosome biogenesis and p53-dependent cell death | 25913037 |
| 2012-09-22 10:22:00 | SIRT7 knockdown leads to reduced levels of RNA Pol I protein, but not messenger RNA | 22586326 |
| 2012-07-07 10:51:00 | findings demonstrate that Bloom's syndrome helicase (BLM)interacts with RPA194; studies suggest that nucleolar BLM modulates rDNA structures in association with RNA polymerase I to facilitate RNA polymerase I-mediated rRNA transcription | 22106380 |
| Type | IDs |
|---|---|
| Synonymous | A190, AFDCIN, RPA1, RPA194, RPO1-4, RPO14 |
| Gene |
UniProtKB-ID:
RPA1_HUMAN
UniprotKB:
O95602
UniParc:
UPI0000D7DB86
EMBL:
U33460,
BC126303,
CH471053,
BC117173,
AL117467,
AK302458,
AH007280
Ensembl:
ENSG00000068654
KO:
hsa:25885
|
| Nucleutide sequences |
EMBL-CDS:
AAI26304.1,
AAI17174.1,
EAW99467.1,
EAW99469.1,
AAC99959.1,
CAB55942.1,
BAH13716.1,
AAD09356.1
Ensembl_TRS:
ENST00000263857
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263857
RefSeq:
NP_056240.2
|
| Others |
UniRef100:
UniRef100_O95602
UniRef90:
UniRef90_O95602
UniRef50:
UniRef50_O95602
UniGene:
Hs.531818
CCDS:
CCDS42706.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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