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25874 MPC2

25874

MPC2

mitochondrial pyruvate carrier 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition mitochondrial pyruvate carrier 2

研究结论

Date Results Publications
2021-02-27 13:50:00 Characteristic Analysis of Homo- and Heterodimeric Complexes of Human Mitochondrial Pyruvate Carrier Related to Metabolic Diseases. 32403431
2021-02-13 13:28:00 The Multifaceted Pyruvate Metabolism: Role of the Mitochondrial Pyruvate Carrier. 32708919
2019-09-14 11:20:00 In contrast to MPC1, which co-purifies with a host chaperone, we demonstrated that MPC2 homo-oligomers promote efficient pyruvate transport into proteoliposomes. The derived functional requirements and kinetic features of MPC2 resemble those previously demonstrated for MPC in the literature 29472561
2019-03-09 10:41:00 MPC2 rs10489202 was genome-wide significantly associated with schizophrenia. The expression quantitative trait loci analysis in lymphoblastoid cell lines from East Asian donors revealed that MPC2 rs10489202 was specifically and significantly associated with the expression of TIPRL gene. 30087317
2019-01-12 12:20:00 The data demonstrated that CtBP1 directly bound to the promoters of MPC1 and MPC2 and transcriptionally repressed them, leading to increased levels of free NADH in the cytosol and nucleus, thus positively feeding back CtBP1's functions. 30356033

名称对应

Type IDs
Synonymous BRP44, SLC54A2
Gene
UniProtKB-ID: MPC2_HUMAN, A0A024R8Z5_HUMAN
UniprotKB: O95563, A0A024R8Z5
UniParc: UPI0000044E0B
EMBL: AL035304, CR407632, Z97876, AL110297, CH471067, AK290126, BC104157, BC104158, CR533473
Ensembl: ENSG00000143158
KO: hsa:25874
Nucleutide sequences
EMBL-CDS: CAG28560.1, CAA22909.1, AAI04158.1, BAF82815.1, CAB53738.1, EAW90814.1, CAG38504.1, AAI04159.1, EAW90815.1, EAW90816.1
Gene_ORFName: hCG_2025634
Ensembl_TRS: ENST00000367846, ENST00000271373
Protein sequencees
Ensembl_PRO: ENSP00000356820, ENSP00000271373
RefSeq: XP_006711329.1, NP_001137146.1, NP_056230.1
Others
UniRef100: UniRef100_O95563
UniRef90: UniRef90_O95563
UniRef50: UniRef50_O95563
UniGene: Hs.517768
CCDS: CCDS1266.1

全选

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