| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 49 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 10:52:00 | USP49 positively regulated dual-specificity protein phosphatases 1 (DUSP1) expression through deubiquitinating DUSP1 | 30246457 |
| 2020-02-08 10:36:00 | USP49 inhibits non-small cell lung cancer cell growth by suppressing PIK3R2/AKT signaling. | 31001918 |
| 2020-02-01 10:42:00 | Here, the authors found that USP49 directly interacts with APOBEC3G and efficiently removes ubiquitin, consequently increasing APOBEC3G protein expression and significantly enhancing its anti-HIV-1 activity. | 31397674 |
| 2019-11-09 11:57:00 | These findings suggest that USP49 has an important role in DNA damage response and may act as a potential tumor suppressor by forming a positive feedback loop with p53. | 29748582 |
| 2017-07-15 10:45:00 | Mechanistically, USP49 deubiquitinates and stabilizes FKBP51, which in turn enhances PHLPP's capability to dephosphorylate AKT. | 28363942 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
UBP49_HUMAN
UniprotKB:
Q70CQ1
UniParc:
UPI00000738AB,
UPI000020DCE0
EMBL:
BC014176,
AL365205,
CH471081,
AJ586139
Ensembl:
ENSG00000164663
KO:
hsa:25862
|
| Nucleutide sequences |
EMBL-CDS:
AAH14176.1,
CAE51939.1,
EAX04065.1
Ensembl_TRS:
ENST00000373006,
ENST00000394253
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362097,
ENSP00000377797
RefSeq:
NP_061031.2,
NP_001371471.1,
NP_001273483.1
|
| Others |
UniRef100:
UniRef100_Q70CQ1
UniRef90:
UniRef90_Q70CQ1
UniRef50:
UniRef50_Q9H0E7
UniGene:
Hs.665742
CCDS:
CCDS4861.1,
CCDS69111.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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