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25843 MOB4

25843

MOB4

MOB family member 4, phocein

protein-coding

Homo sapiens

基因描述

Type Description
Definition MOB family member 4, phocein

研究结论

Date Results Publications
2019-04-13 12:23:00 Because of divergent evolution of key interface residues, MST4 and MOB4 could disrupt assembly of the MST1-MOB1 complex through alternative pairing and thereby increased YAP activity. Collectively, these findings identify the MST4-MOB4 complex as a noncanonical regulator of the Hippo-YAP pathway with an oncogenic role in PC 30072378
2014-09-27 10:13:00 hMOB3 modulates MST1 apoptotic signaling and supports tumor growth in glioblastoma multiforme. 24872389
2010-01-21 00:00:00 phosphorylation of MOB1 at Thr74 by MST2 is essential to make a complex of MOB1, MST2 and NDR1, and to fully activate NDR1 18362890

名称对应

Type IDs
Synonymous 2C4D, CGI-95, MOB1, MOB3, MOBKL3, PHOCN, PREI3
Gene
UniProtKB-ID: PHOCN_HUMAN, A0A024R3X9_HUMAN
UniprotKB: Q9Y3A3, A0A024R3X9
UniParc: UPI000002276F, UPI000006F475, UPI00005E7A7F
EMBL: AL080070, AF250319, AK027043, AB015441, AF151853, BC005237, AJ580638, AF093825, CR457371, AK297514, AK292938, AC020550, CH471063
Ensembl: ENSG00000115540
KO: hsa:25843
Nucleutide sequences
EMBL-CDS: BAF85627.1, BAB15635.1, CAE45270.1, CAG33652.1, EAW70164.1, CAB45697.1, AAH05237.1, AAX93147.1, AAP97221.1, AAG44567.1, BAB19057.1, AAD34090.1, EAW70167.1, BAG59922.1, EAW70168.1
Gene_ORFName: CGI-95, hCG_20091
Ensembl_TRS: ENST00000409360, ENST00000448447, ENST00000233892, ENST00000323303
Protein sequencees
Ensembl_PRO: ENSP00000233892, ENSP00000387289, ENSP00000315702, ENSP00000405354
RefSeq: NP_955776.1, NP_001191023.1, NP_056202.2, NP_001094289.1
Others
UniRef100: UniRef100_Q9Y3A3
UniRef90: UniRef90_Q9Y3A3
UniRef50: UniRef50_Q9Y3A3
UniGene: Hs.633165
CCDS: CCDS2321.1, CCDS2322.1, CCDS46480.1

全选

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