| Type | Description |
|---|---|
| Definition | beta-1,4-N-acetyl-galactosaminyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 13:24:00 | B4GALNT1 enhanced tumorigenesis via induction of angiogenesis,ganglioside GM2/GD2 and cell motility. | 31988291 |
| 2020-02-29 10:57:00 | Data suggest that GD2 synthase (GD2) can well be considered as a diagnostic and prognostic marker in breast cancer. | 31075227 |
| 2019-10-05 12:04:00 | High B4GALNT1 expression is associated with clear cell renal cell carcinoma metastasis. | 31491435 |
| 2019-04-20 12:21:00 | Sp1 or HDAC1 knock down increased GM2-synthase transcription, and butyrate-mediated activation of GM2-synthase mRNA expression in SK-RC-45 cells was accompanied by Sp1 and HDAC1 loss from the +38/+187 region. Taken together, we have identified an epigenetic mechanism for the de-repression of the GM2-synthase gene in RCC. | 30463940 |
| 2019-03-23 10:58:00 | Since the nineties, mice lacking genes for single glycosyltransferases involved in ganglioside biosynthesis, including ST3GAL5 and B4GALNT1, were created and studied. The resulting phenotypes were frequently mild or very mild, so double knock-out animals were created to effectively study the function of gangliosides | 29983310 |
| Type | IDs |
|---|---|
| Synonymous | GALGT, GALNACT, GalNAc-T, SPG26 |
| Gene |
UniProtKB-ID:
B4GN1_HUMAN,
B4DSP5_HUMAN
UniprotKB:
Q00973,
B4DSP5
UniParc:
UPI00017A6C49,
UPI0000126DD5,
UPI000006F693,
UPI00017A7BF4
EMBL:
BC029828,
M83651,
AK293432,
AC025165,
AK299845
Ensembl:
ENSG00000135454
KO:
hsa:2583
|
| Nucleutide sequences |
EMBL-CDS:
AAH29828.1,
BAG56937.1,
AAA35516.1,
BAG61707.1
Ensembl_TRS:
ENST00000552350,
ENST00000550764,
ENST00000418555,
ENST00000341156,
ENST00000449184
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000450303,
ENSP00000448500,
ENSP00000401601,
ENSP00000341562,
ENSP00000473533
RefSeq:
NP_001263397.1,
XP_024304696.1,
XP_016874629.1,
XP_016874631.1,
XP_011536449.1,
XP_005268830.1,
NP_001263398.1,
XP_024304697.1,
NP_001469.1,
XP_016874630.1
|
| Others |
UniRef100:
UniRef100_B4DSP5,
UniRef100_Q00973
UniRef90:
UniRef90_B4DSP5,
UniRef90_Q00973
UniRef50:
UniRef50_Q00973-3,
UniRef50_Q00973
UniGene:
Hs.159481
CCDS:
CCDS61170.1,
CCDS61171.1,
CCDS8950.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员