| Type | Description |
|---|---|
| Definition | nocturnin |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:32:00 | Differential processing and localization of human Nocturnin controls metabolism of mRNA and nicotinamide adenine dinucleotide cofactors. | 32839274 |
| 2020-01-25 14:49:00 | Measuring NOCTURNIN expression levels in human peripheral blood lymphocytes can improve investigations on the relationship between changes in circadian rhythm and metabolic disorders. Shift workers show higher NOCTURNIN levels than daytime worker | 31467910 |
| 2019-11-30 11:59:00 | Study present a 2.7-A crystal structure of the catalytic domain of human NOCT. Our structure shows that NOCT has a close overall similarity to CCR4 deadenylase family members, PDE12 and CNOT6L, and to a DNA repair enzyme TDP2. All the key catalytic residues present in PDE12, CNOT6L and TDP2 are conserved in NOCT and have the same conformations. | 30389976 |
| 2019-08-03 12:46:00 | NOCT is an exoribonuclease that can degrade mRNAs to inhibit protein expression | 29860338 |
| 2019-01-12 11:56:00 | This review seeks to integrate these new discoveries into our understanding of Nocturnin's regulatory functions and highlight the important remaining unanswered questions surrounding its regulation, biochemical activities, protein partners, and target mRNAs. | 30257600 |
| Type | IDs |
|---|---|
| Synonymous | CCR4L, CCRN4L, Ccr4c, NOC |
| Gene |
UniProtKB-ID:
NOCT_HUMAN
UniprotKB:
Q9UK39
UniParc:
UPI000013DC2C
EMBL:
CH471056,
AF183961,
BC113500,
AF199493,
BC113494,
AF199494,
AF199492
Ensembl:
ENSG00000151014
KO:
hsa:25819
|
| Nucleutide sequences |
EMBL-CDS:
EAX05129.1,
EAX05131.1,
AAG01387.1,
AAI13495.1,
AAG01389.1,
AAG01388.1,
AAD56548.1,
AAI13501.1
Ensembl_TRS:
ENST00000280614
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000280614
RefSeq:
NP_036250.2
|
| Others |
UniRef100:
UniRef100_Q9UK39
UniRef90:
UniRef90_Q9UK39
UniRef50:
UniRef50_Q9UK39
UniGene:
Hs.639842,
Hs.656047
CCDS:
CCDS3743.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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