| Type | Description |
|---|---|
| Definition | galactosylceramidase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:23:00 | beta-Galactosylceramidase Promotes Melanoma Growth via Modulation of Ceramide Metabolism. | 32998995 |
| 2020-11-21 13:19:00 | Brainstem development requires galactosylceramidase and is critical for pathogenesis in a model of Krabbe disease. | 33097716 |
| 2020-05-23 10:57:00 | This study generated information on the recessive allele frequency dynamics of GALC gene across 15 global populations. | 32304783 |
| 2020-04-11 12:49:00 | Self-association of beta-galactocerebrosidase (human GALC)decreases as the concentration of sodium chloride increases from 50 to 500 mM. This indicates that ionic interactions are involved in the association. These results indicate that GALC has the highest tendency for oligomerization at physiological ionic strength and pH (lysosomal lumen). | 31869371 |
| 2019-08-10 10:53:00 | The present study describes two GALC mutations shared by two Chinese siblings with juvenile-onset of Krabbe disease | 31185936 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GALC_HUMAN,
A0A0A0MQV0_HUMAN
UniprotKB:
P54803,
A0A0A0MQV0
UniParc:
UPI00019B21FD,
UPI00001FD982,
UPI00004DD150,
UPI0001F5506D
EMBL:
AL157955,
AL136501,
L23116,
L38558,
L38549,
L38551,
L38550,
BC036518,
D25284,
L38547,
HM005711,
L38553,
AK302519,
AK302956,
L38556,
AK296530,
L38544,
L38559,
L38555,
L38557,
L38545,
AK302683,
L38546,
HM005712,
D86181,
D25283,
L38548,
L38552
Ensembl:
ENSG00000054983
KO:
hsa:2581
|
| Nucleutide sequences |
EMBL-CDS:
BAA04972.1,
BAA24902.1,
AAA80975.1,
BAG59160.1,
AAA16645.1,
BAA04971.1,
BAG64110.1,
BAG63793.1,
AAH36518.1,
BAH13778.1,
AEE61308.1,
AEE61309.1
Ensembl_TRS:
ENST00000261304,
ENST00000544807,
ENST00000393569,
ENST00000393568
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000377198,
ENSP00000437513,
ENSP00000261304,
ENSP00000377199
RefSeq:
XP_011534920.1,
NP_001188331.1,
NP_001188330.1,
NP_000144.2
|
| Others |
UniRef100:
UniRef100_P54803
UniRef90:
UniRef90_P54803
UniRef50:
UniRef50_P54803
UniGene:
Hs.513439
CCDS:
CCDS55936.1,
CCDS55937.1,
CCDS9878.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员