| Type | Description |
|---|---|
| Definition | leiomodin 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-02 10:03:00 | rs34091558 is the top regulatory variant for LMOD1 in vascular tissues. This genetic variation is associated with dysregulated LMOD1 expression/function in smooth muscle cells, contributing to the heritable risk for coronary artery disease. | 30444878 |
| 2018-05-12 11:57:00 | Loss of LMOD1 results in a reduction of filamentous actin, elongated cytoskeletal dense bodies, and impaired intestinal smooth muscle contractility. | 28292896 |
| 2017-07-15 11:31:00 | Key role for miR-214 in modulation of MEF2C-MYOCD-LMOD1 signaling. | 27144530 |
| 2017-06-24 10:10:00 | LMOD1, SYNPO2, PDLIM7, PLN, and SYNM down-regulation reflect the altered phenotype of smooth muscle cells in vascular disease and could be early sensitive markers of SMC dedifferentiation. | 27470516 |
| 2012-03-17 12:24:00 | Lmod1 is a new SMC-restricted SRF/MYOCD target gene. | 22157009 |
| Type | IDs |
|---|---|
| Synonymous | 1D, 64kD, D1, SM-LMOD, SMLMOD |
| Gene |
UniProtKB-ID:
LMOD1_HUMAN
UniprotKB:
P29536
UniParc:
UPI0000E06036,
UPI00003665F4
EMBL:
X54162,
AL513217,
AC099676,
BC080187
Ensembl:
ENSG00000163431
KO:
hsa:25802
|
| Nucleutide sequences |
EMBL-CDS:
AAH80187.1,
CAA38101.1
Ensembl_TRS:
ENST00000367288
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356257
RefSeq:
NP_036266.2
|
| Others |
UniRef100:
UniRef100_P29536
UniRef90:
UniRef90_P29536
UniRef50:
UniRef50_P29536
UniGene:
Hs.519075
CCDS:
CCDS53457.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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