| Type | Description |
|---|---|
| Definition | small VCP interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:27:00 | SVIP is a molecular determinant of lysosomal dynamic stability, neurodegeneration and lifespan. | 33479240 |
| 2020-04-11 12:41:00 | Overexpression of SVIP can protect HepG2 cells from the toxicity of CCl4, which could be enhanced by starvation. | 30683843 |
| 2017-09-09 10:38:00 | overexpression of gp78 or SVIP suppression may eliminate the toxic gain of function associated with polymerization of ZAAT, thus providing a potential new therapeutic approach to the treatment of alpha-1 antitrypsin deficiency | 28301499 |
| 2014-02-22 11:47:00 | the interactions between P97 and these motifs, including VCP-binding motif (VBM) and VCP-interacting motif (VIM). The solution structures of the VBM motif from HRD1 and the VIM motif from SVIP are both comprised mainly of a single alpha-helix. | 24100225 |
| 2013-12-07 10:08:00 | A major portion of SVIP is intrinsically disordered in solution. | 24055875 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SVIP_HUMAN
UniprotKB:
Q8NHG7
UniParc:
UPI000006DD71
EMBL:
AF527534
Ensembl:
ENSG00000198168
KO:
hsa:258010
|
| Nucleutide sequences |
EMBL-CDS:
AAM88869.1
Ensembl_TRS:
ENST00000354193
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000346130
RefSeq:
XP_024304191.1,
NP_683691.1,
NP_001307269.1,
NP_001307270.1,
NP_001307271.1
|
| Others |
UniRef100:
UniRef100_Q8NHG7
UniRef90:
UniRef90_Q8NHG7
UniRef50:
UniRef50_Q8NHG7
UniGene:
Hs.349096
CCDS:
CCDS41627.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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