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25801 GCA

25801

GCA

grancalcin

protein-coding

Homo sapiens

基因描述

Type Description
Definition grancalcin

研究结论

Date Results Publications
2020-07-18 10:26:00 GCA activates TRAF6 ubiquitin ligase activity to induce Lys63 ubiquitination of ULK1, a crucial regulator of autophagy, resulting in its stabilization and activation. It was also highlighted the role of GCA-TRAF6-ULK1 autophagy regulatory axis in imatinib resistance. 30929559
2016-08-06 11:12:00 Results indicate that heterodimerization of GCA and TLR9 is important for TLR9-mediated downstream signaling and might serve to fine tune processes against viral infection. 26648480
2010-12-05 22:08:00 Observational study of gene-disease association. (HuGE Navigator) 20800603
2010-04-07 21:39:00 Observational study of gene-disease association. (HuGE Navigator) 20237496
2010-01-21 00:00:00 GCA interacts with SRI in vivo and in vitro. 12804766

名称对应

Type IDs
Synonymous GCL
Gene
UniProtKB-ID: GRAN_HUMAN, B7Z322_HUMAN, H7BXD5_HUMAN
UniprotKB: P28676, B7Z322, H7BXD5
UniParc: UPI000012BA7D, UPI0000421DAF, UPI0000469C39
EMBL: BC005214, AC010876, CH471058, AK295413, AK312349, M81637, AB209768
Ensembl: ENSG00000115271
KO: hsa:25801
Nucleutide sequences
EMBL-CDS: AAH05214.1, AAA58498.1, BAG35270.1, AAX93138.1, EAX11350.1, BAD93005.1, BAH12058.1
Ensembl_TRS: ENST00000437150, ENST00000233612
Protein sequencees
Ensembl_PRO: ENSP00000394842, ENSP00000233612
RefSeq: NP_001317199.1, XP_006712461.1, NP_036330.1, NP_001317195.1, XP_006712463.1, XP_005246503.1, XP_011509230.1, NP_001317197.1, XP_016859256.1, XP_016859258.1, NP_001317196.1, NP_001317194.1, NP_001317200.1, XP_011509228.1
Others
UniRef100: UniRef100_Q5RB53, UniRef100_H7BXD5, UniRef100_P28676
UniRef90: UniRef90_A0A2I3TL92, UniRef90_P28676
UniRef50: UniRef50_P28676, UniRef50_F1PJS2
UniGene: Hs.377894
CCDS: CCDS2218.1

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