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25800 SLC39A6

25800

SLC39A6

solute carrier family 39 member 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 39 member 6

研究结论

Date Results Publications
2021-03-06 13:27:00 The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis. 32797246
2020-05-09 12:07:00 ZIP10 is predominantly expressed in the interfollicular epidermis, epidermal appendages and hair follicles. ZIP10 depletion resulted in epidermal malformations in a reconstituted human skin model via downregulation of the epigenetic enzyme histone acetyltransferase (HAT). Decreased HAT activity, resulting from either ZIP10 depletion or treatment with the zinc chelator TPEN, was readily restored by zinc supplementation. 30339739
2020-04-11 10:59:00 SLC39A6 is involved in gastric adenocarcinoma, and genotype at SLC39A6 rs1050631 can predict post-resection prognosis of gastric adenocarcinoma patients, at least in a population in an area with high gastric adenocarcinoma incidence. 31703635
2020-04-04 12:19:00 These data demonstrate that LIV-1-GRPEL1 axis dually regulates mitotic exit as well as apoptosis by interacting with PP2A B55alpha and AIF. 31636012
2019-11-02 10:41:00 this work shows that zinc entry into activated lymphocytes depends on Zip6 and that this transporter is essential for the correct function of the cellular activation machinery 30552163

名称对应

Type IDs
Synonymous LIV-1, ZIP6
Gene
UniProtKB-ID: S39A6_HUMAN
UniprotKB: Q13433
UniParc: UPI0000074356, UPI000004EC93
EMBL: AK304079, AK299102, AC091060, U41060, CH471088, BC039498, BC008317
Ensembl: ENSG00000141424
KO: hsa:25800
Nucleutide sequences
EMBL-CDS: BAG61161.1, AAA96258.2, EAX01372.1, AAH39498.1, AAH08317.2, BAG64986.1
Ensembl_TRS: ENST00000590986, ENST00000269187, ENST00000440549
Protein sequencees
Ensembl_PRO: ENSP00000465915, ENSP00000269187, ENSP00000401139
RefSeq: NP_036451.4, XP_011524202.1, NP_001092876.1, XP_011524203.1
Others
UniRef100: UniRef100_Q13433
UniRef90: UniRef90_Q13433
UniRef50: UniRef50_Q13433
UniGene: Hs.79136
CCDS: CCDS42428.1, CCDS45854.1

全选

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研究热度

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