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2580 GAK

2580

GAK

cyclin G associated kinase

protein-coding

Homo sapiens

基因描述

Type Description
Definition cyclin G associated kinase

研究结论

Date Results Publications
2020-10-24 14:09:00 Dynamics of Auxilin 1 and GAK in clathrin-mediated traffic. 31962345
2018-04-28 10:34:00 These findings indicate that the abnormal mitoses seen after silencing OIP5-AS1 were caused by an untimely rise in GAK levels and suggest that OIP5-AS1 suppresses cell proliferation at least in part by reducing GAK levels. 28472763
2017-12-30 10:56:00 that the multiple single nucleotide polymorphisms of GAK synergistically participate in the pathogenesis of sporadic Parkinson's disease through multiple pathways. 26676575
2017-10-07 11:44:00 We have demonstrated that siRNA-mediated GAK silencing causes marked cell cycle disruption resulting in a raised sub-G1 alongside decreased G1 and G2/M cell cycle phases. Dual FBXW7-GAK inhibition increases multipolar mitoses 28829765
2017-08-26 12:20:00 GAK gene expression is increased in Parkinson disease 27508417

名称对应

Type IDs
Synonymous DNAJ26, DNAJC26
Gene
UniProtKB-ID: GAK_HUMAN, B4DS37_HUMAN
UniprotKB: O14976, B4DS37
UniParc: UPI000020B996, UPI00017A7C12, UPI000012B04A
EMBL: D88435, AK299554, BC000816, BC008668, BC085005
Ensembl: ENSG00000178950
KO: hsa:2580
Nucleutide sequences
EMBL-CDS: AAH00816.1, AAH08668.1, BAA22623.1, AAH85005.1, BAG61499.1
Ensembl_TRS: ENST00000314167, ENST00000511163
Protein sequencees
Ensembl_PRO: ENSP00000421361, ENSP00000314499
RefSeq: XP_011511734.1, XP_011511733.1, XP_016863483.1, XP_011511727.1, XP_011511729.1, XP_011511730.1, XP_016863480.1, XP_011511732.1, XP_011511736.1, XP_005272327.1, NP_005246.2, XP_016863482.1, XP_005272325.1, XP_011511731.1, XP_016863481.1, NP_001305063.1, XP_016863484.1, XP_011511728.1
Others
UniRef100: UniRef100_O14976, UniRef100_B4DS37
UniRef90: UniRef90_O14976
UniRef50: UniRef50_O14976
UniGene: Hs.369607
CCDS: CCDS82902.1, CCDS3340.1

全选

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