| Type | Description |
|---|---|
| Definition | ameloblastin |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:49:00 | Ameloblastin is critical for the initiation of enamel ribbon formation, and its absence results in pathological mineralization within the enamel organ epithelia. | 31402633 |
| 2018-09-08 12:10:00 | Single nucleotide polymorphisms in the AMELX and AMBN genes may be genetic variants that contribute to developmental defects of enamel in primary dentition of Polish children. | 28382465 |
| 2018-06-30 11:52:00 | the calcium level was associated with genetic variations in AMELX, AMNB and ESRRB. AMELX and AMNB are involved in enamel mineralization. Mutations in both these genes are responsible for the amelogenesis imperfecta phenotype (OMIN), which supports their link with enamel alterations as well as enamel mineralization. | 28395292 |
| 2017-12-23 10:19:00 | these results indicate that AMBN enhances IL-1beta production in LPS-treated U937 cells through ERK1/2 phosphorylation and caspase-1 activation, suggesting that AMBN upregulates the inflammatory response in human macrophages and plays an important role in innate immunity. | 28295583 |
| 2016-11-12 10:29:00 | Association between caries experience (caries-free versus caries affected) depending on asthma status and SNPs was tested. Logistic regression showed an association between AMBN rs4694075 and caries experience. Ameloblastin is associated w/caries in asthmatic children. | 24203249 |
| Type | IDs |
|---|---|
| Synonymous | AI1F |
| Gene |
UniProtKB-ID:
AMBN_HUMAN,
Q546D7_HUMAN
UniprotKB:
Q9NP70,
Q546D7
UniParc:
UPI000002A3A0,
UPI000000DCCB
EMBL:
AY009116,
AF263464,
AK314918,
AJ537437,
AY009118,
AY009121,
AF209780,
BC106931,
AY009120,
AY009124,
AY009122,
AY009123,
AF219994,
AY009117,
AY009119
Ensembl:
ENSG00000178522
KO:
hsa:258
|
| Nucleutide sequences |
EMBL-CDS:
AAI06932.1,
AAG27036.1,
AAG35772.1,
AAF73048.1,
AAF37355.1,
BAG37429.1,
CAD60938.1
Ensembl_TRS:
ENST00000449493,
ENST00000322937
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000391234,
ENSP00000313809
RefSeq:
NP_057603.1
|
| Others |
UniRef100:
UniRef100_Q9NP70
UniRef90:
UniRef90_Q9NP70
UniRef50:
UniRef50_Q9NP70
UniGene:
Hs.272396
CCDS:
CCDS3543.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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