| Type | Description |
|---|---|
| Definition | RAS guanyl releasing protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-21 11:02:00 | RasGRP3, a Ras guanyl releasing protein 3 that contributes to malignant proliferation and aggressiveness in human esophageal squamous cell carcinoma | 29461644 |
| 2018-07-07 10:19:00 | In conclusion, these findings provide a new insight into the upregulation of RasGRP3 involved in Notch pathway activation in the development of esophageal squamous cell carcinoma , especially under nutrient deprivation. | 29048643 |
| 2018-02-10 10:33:00 | The marked differences between RasGRP3 and RasGRP1 in membrane interaction necessarily will contribute to their different behavior in cells. | 28912101 |
| 2017-09-30 12:34:00 | these data show that RasGRP3 exerts its oncogenic effect in papillary thyroid cancer through Akt-mediated MDM2 activation. | 28864115 |
| 2017-08-26 12:36:00 | RasGRP3 mediates ERK MAPK pathway activation in GNAQ mutant uveal melanoma. | 28486107 |
| Type | IDs |
|---|---|
| Synonymous | GRP3 |
| Gene |
UniProtKB-ID:
GRP3_HUMAN
UniprotKB:
Q8IV61
UniParc:
UPI000006EFC8,
UPI0000074694
EMBL:
CH471053,
BX647990,
AC020594,
AB020653,
BC027849
Ensembl:
ENSG00000152689
KO:
hsa:25780
|
| Nucleutide sequences |
EMBL-CDS:
BAA74869.2,
AAH27849.1,
EAX00433.1,
AAY15037.1,
EAX00432.1,
EAX00434.1
Ensembl_TRS:
ENST00000403687,
ENST00000407811,
ENST00000402538
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000383917,
ENSP00000385886,
ENSP00000384192
RefSeq:
XP_011531050.2,
NP_001336905.1,
NP_001336908.1,
XP_016859250.1,
NP_001336904.1,
NP_001336909.1,
NP_001336910.1,
NP_001336907.1,
XP_016859248.1,
NP_001336906.1,
XP_011531048.1,
NP_733772.1,
NP_056191.1,
NP_001132960.1
|
| Others |
UniRef100:
UniRef100_Q8IV61
UniRef90:
UniRef90_Q8IV61
UniRef50:
UniRef50_Q8IV61
UniGene:
Hs.143674
CCDS:
CCDS46256.1,
CCDS54346.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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