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25777 SUN2

25777

SUN2

Sad1 and UNC84 domain containing 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition Sad1 and UNC84 domain containing 2

研究结论

Date Results Publications
2021-03-06 13:25:00 Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes. 33058875
2021-01-16 15:59:00 SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells. 31935926
2019-03-09 11:40:00 a fragment of SUN2 containing CC1, CC2, and the SUN domain model is reported. 29995584
2019-01-26 11:13:00 SUN2 is a novel chromatin reassembly factor that helps to maintain chromatin in a repressive state and consequently inhibits HIV-1 transcription. 29717016
2018-12-22 11:08:00 While Sun1 and Sun2 in HeLa cells are each able to bind KASH-domains, Sun1 is more efficiently incorporated into LINC complexes under normal growth conditions. Furthermore, the balance of Sun1 and Sun2 incorporated into LINC complexes is cell type-specific and is correlated with SRF/Mkl1-dependent gene expression. 29813079

名称对应

Type IDs
Synonymous UNC84B
Gene
UniProtKB-ID: SUN2_HUMAN, A0A024R1P7_HUMAN, B4E2A6_HUMAN
UniprotKB: Q9UH99, A0A024R1P7, B4E2A6
UniParc: UPI00017A86F8, UPI0001611146, UPI000067CA68, UPI0000137937
EMBL: BC111717, CH471095, AL021707, CR456474, BC111549, AY682988, AL008583, BC094797, BC030684, AF202723, AK304188, AB014568, BX537962, AL021806
Ensembl: ENSG00000100242
KO: hsa:25777
Nucleutide sequences
EMBL-CDS: AAT90500.1, AAF15887.1, AAH94797.1, BAA31643.1, CAG30360.1, AAI11550.1, AAH30684.2, AAI11718.1, CAD97926.1, EAW60268.1, EAW60266.1, EAW60270.1, BAG65068.1
Gene_ORFName: hCG_41706
Ensembl_TRS: ENST00000405018, ENST00000405510, ENST00000406622
Protein sequencees
Ensembl_PRO: ENSP00000383992, ENSP00000385616, ENSP00000385740
RefSeq: NP_056189.1, NP_001186508.1, XP_024307972.1, XP_011528407.1, XP_024307974.1, XP_011528406.1, NP_001186509.1, XP_016884237.1, XP_024307971.1, XP_024307973.1
Others
UniRef100: UniRef100_Q9UH99, UniRef100_B4E2A6
UniRef90: UniRef90_Q9UH99
UniRef50: UniRef50_Q9UH99
UniGene: Hs.517622, Hs.744734
CCDS: CCDS13978.1, CCDS56231.1

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