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25776 CBY1

25776

CBY1

chibby family member 1, beta catenin antagonist

protein-coding

Homo sapiens

基因描述

Type Description
Definition chibby family member 1, beta catenin antagonist

研究结论

Date Results Publications
2019-12-14 10:18:00 Chibby expression was decreased in gastric cancer samples and altered beta-catenin localization in cultured gastric cancer cells. 30063079
2019-05-11 10:56:00 Our study reveals an association between Chibby expression and cancer aerobic glycolysis, which highlights the importance of Wnt/beta-catenin pathway in regulation of energy metabolism of NPC. These results indicate that Chibby and PDK1 are the potential target for NPC treatment. 29764469
2017-06-24 11:36:00 FAM92 proteins interact with Cby1 to promote ciliogenesis via regulation of membrane-remodeling processes. 27528616
2017-06-24 11:14:00 chronic Cby1 knockdown in colon cancer cells may counteract tumor progression by promoting the mesenchymal-to-epithelial transition process. 28107095
2017-04-22 11:30:00 Cby's C-terminal domain alone binds to TC-1 with significantly greater affinity compared to full-length Cby, implying that target binding of the coiled-coil domain is affected by the flanking disordered regions. 27082063

名称对应

Type IDs
Synonymous C22orf2, CBY, Chibby1, HS508I15A, PGEA1, PIGEA-14, PIGEA14, arb1
Gene
UniProtKB-ID: CBY1_HUMAN, A0A087WUW0_HUMAN, A0A024R1L9_HUMAN
UniprotKB: Q9Y3M2, A0A087WUW0, A0A024R1L9
UniParc: UPI0000128720, UPI000047F760
EMBL: CR456410, AF331041, AB111855, AL021707, CH471095, AL136686, BK005534, AL050345, AB015347, BC016139, AK311928
Ensembl: ENSG00000100211
KO: hsa:25776
Nucleutide sequences
EMBL-CDS: EAW60254.1, BAG34869.1, AAH16139.1, CAG30296.1, BAA88119.1, CAB66621.1, AAL56062.1, CAB43547.1, BAC78839.1, DAA05582.1, EAW60256.1, EAW60255.1
Gene_ORFName: HRIHFB2025, hCG_2010808
Ensembl_TRS: ENST00000396811, ENST00000216029, ENST00000619293
Protein sequencees
Ensembl_PRO: ENSP00000380026, ENSP00000216029, ENSP00000478962
RefSeq: NP_056188.1, NP_001002880.2
Others
UniRef100: UniRef100_Q9Y3M2
UniRef90: UniRef90_Q9Y3M2
UniRef50: UniRef50_Q9Y3M2
UniGene: Hs.334911, Hs.744261
CCDS: CCDS13974.1

全选

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