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25757 Cpt1a

25757

Cpt1a

carnitine palmitoyltransferase 1A

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition carnitine palmitoyltransferase 1A

研究结论

Date Results Publications
2020-06-20 10:29:00 CPT1a downregulation protects against 7-ketocholesterol-induced fibrosis in tubular epithelial cells by downregulating TGF-beta1, alpha- SMA and NLRP3. 31405564
2020-02-15 11:52:00 A significant up-regulation of Cpt1a, Acadl and Sirt3, all beta-oxidation genes, along with a significant deacetylation of the forkhead transcription factor 3a (FOXO3A) was found in alpha-LA-treated animals. 30764676
2019-08-10 10:40:00 dietary fat elevates hepatic Cpt1a expression via a highly coordinated transcriptional mechanism involving increased H3K4Me2, reduced DNAMe, and recruitment of C/EBPbeta, PPARalpha, PGC1alpha, and BAF60a to the gene. 30605728
2018-07-14 10:41:00 Obesity-alleviating potential of asiatic acid and its effects on ACC1, UCP2, and CPT1 mRNA expression in high fat diet-induced obese Sprague-Dawley rats 28993954
2017-08-26 11:32:00 Furthermore, given the already low abundance of Cpt1b in white adipose tissue, it is unlikely that decreases in its expression can quantitatively decrease whole body energy expenditure enough to contribute to an obese phenotype. 28330968

名称对应

Type IDs
Synonymous CPT-Ia
Gene
UniProtKB-ID: CPT1A_RAT
UniprotKB: P32198
UniParc: UPI0000170B82
EMBL: U88294, L07736, BC072522
Ensembl: ENSRNOG00000014254
KO: rno:25757
Nucleutide sequences
EMBL-CDS: AAA40876.1, AAH72522.1, AAB48046.1
Ensembl_TRS: ENSRNOT00000019652
Protein sequencees
Ensembl_PRO: ENSRNOP00000019652
RefSeq: XP_017444326.1, XP_006230757.1, NP_113747.2, XP_017444327.1
Others
UniRef100: UniRef100_P32198
UniRef90: UniRef90_P32198
UniRef50: UniRef50_P32198
UniGene: Rn.2856

全选

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研究热度

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