| Type | Description |
|---|---|
| Definition | HCK proto-oncogene, Src family tyrosine kinase |
| Date | Results | Publications |
|---|---|---|
| 2017-02-25 12:31:00 | Hck was up-regulated in neurons adjacent to the hematoma after intracerebral hemorrhage. | 27053350 |
| 2003-09-12 11:53:00 | Alternate protein isoforms arise through the use of a non-AUG (CUG), and a downstream in-frame AUG translation initiation codons, in mouse and human. Same is likely true for rat as there is strong sequence conservation amongst different species. | 1875927 |
| Type | IDs |
|---|---|
| Synonymous | Hctk, p56Hck, p59Hck |
| Gene |
UniProtKB-ID:
HCK_RAT
UniprotKB:
P50545
UniParc:
UPI00001C1A94,
UPI0000402750
EMBL:
X62345,
S74141,
BC078890,
M83666
Ensembl:
ENSRNOG00000009331
KO:
rno:25734
|
| Nucleutide sequences |
EMBL-CDS:
AAB20754.1,
AAA41312.1,
CAA44218.1,
AAH78890.2
Ensembl_TRS:
ENSRNOT00000012432
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000012432
RefSeq:
NP_037317.2
|
| Others |
UniRef100:
UniRef100_P50545
UniRef90:
UniRef90_P08103
UniRef50:
UniRef50_P08103
UniGene:
Rn.10945
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 27053350 |
Hck Promotes Neuronal Apoptosis Following Intracerebral Hemorrhage. Cell. Mol. Neurobiol. Jun Wang , Rongrong Chen , Xiaojuan Liu , Jianhong Shen , Yaohua Yan , Yilu Gao , Tao Tao , Jiansheng Shi |
2017-03-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20624904 |
J. Cell Biol. Adrian Mehlitz , Sebastian Banhart , André P Mäurer , Alexis Kaushansky , Andrew G Gordus , Julia Zielecki , Gavin Macbeath , Thomas F Meyer |
2010-07-12 |
SHC1
|
| 17535448 |
Regulation of p73 by Hck through kinase-dependent and independent mechanisms. BMC Mol. Biol. Preeti Paliwal , Vegesna Radha , Ghanshyam Swarup |
2007-01-01 |
HCK
|
| 16921024 |
Differential kinase requirements in human and mouse Fc-gamma receptor phagocytosis and endocytosis. J. Leukoc. Biol. Zhen-Yu Huang , Daniel R Barreda , Randall G Worth , Zena K Indik , Moo-Kyung Kim , Paul Chien , Alan D Schreiber |
2006-12-01 |
Pik3r1,
Syk,
FGR,
FYN,
HCK,
LYN,
PIK3R1,
SRC,
SYK,
YES1
|
| 15998323 |
Activation of the lysosome-associated p61Hck isoform triggers the biogenesis of podosomes. Traffic Céline Cougoule , Sébastien Carréno , Jerôme Castandet , Arnaud Labrousse , Catherine Astarie-Dequeker , Renaud Poincloux , Véronique Le Cabec , Isabelle Maridonneau-Parini |
2005-08-01 |
HCK
|
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 15060019 |
Genome Res. Anne E Kwitek , Jo Gullings-Handley , Jiaming Yu , Danilo C Carlos , Kimberly Orlebeke , Jeff Nie , Jeffrey Eckert , Angela Lemke , Jaime Wendt Andrae , Susan Bromberg , Dean Pasko , Dan Chen , Todd E Scheetz , Thomas L Casavant , M Bento Soares , Val C Sheffield , Peter J Tonellato , Howard J Jacob |
2004-04-01 |
Hoxa1,
Pitpnb,
Txn1,
Kcnj9,
Phox2a,
Cga,
Gjb4,
Kcnc3,
Nr0b2,
Mgst1,
Sftpb,
Unc50,
Acadm,
Acr,
Adrb2,
Afp,
Akt1,
Aldob,
Akr1b1,
Apeh,
Atp1a3,
Atp2b2,
Atp4b,
Atp7b,
B2m,
Tspo,
C4bpa,
C4bpb,
Calca,
Calm3,
Cat,
Cbs,
Cd53,
Psg19,
Chga,
Chgb,
Ckm,
Comt,
Cryaa,
Cryge,
Prl3b1,
Ctrb1,
Cyp1a1,
Cyp4b1,
Dbp,
Ddc,
Egfr,
Egr1,
Eno1,
Ets1,
Fancc,
Fbp1,
Fuca1,
Gad2,
Gfap,
Gfi1,
Got1,
Grin2b,
Nr3c1,
Hbb,
Hrh1,
Hspa1a,
Htr1a,
Iapp,
Ibsp,
Ifnb1,
Igf1,
Igfbp3,
Il1b,
Il5,
Ins1,
Irf1,
Klk1,
Lepr,
Lpl,
Mbl1,
Me1,
Mpg,
Mt1,
Muc1,
Ncam1,
Mme,
Cgref1,
Cxcl10,
Nos1,
Nppa,
Npy,
Oprd1,
Orm1,
S100a4,
Pah,
Serpine1,
Pgm1,
Pklr,
Prl6a1,
Pmch,
Pomc,
Prkca,
Pthlh
|
| 14551197 |
J Biol Chem R Shivakrupa , Vegesna Radha , Ch Sudhakar , Ghanshyam Swarup |
2003-12-26 | - |
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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